The 6.7M EPSRC Frontier Engineering Award MultiSim is a five-year programme that aims to predict disease development and to enable better treatments for chronic bone disorders, as part of a programme to create a new modelling framework for the human musculoskeletal system. MultiSim is one of the flagship projects of the Insigneo Institute in in silico Medicine in The University of Sheffield, which intends to realise the scientific ambition behind the Virtual Physiological Human, that of producing a transformational impact on healthcare.

The post-holder will use network analysis methods to explore a multiscale model design space applied to predicting bone disease development. Surrogate data sources will be identified from the literature and will be linked to the network within a Bayesian inference paradigm. Global sensitivity analysis will be performed on this augmented network to discover a multiscale model that is more amenable to experimental validation and clinical translation.

Applicants should hold a strong PhD in Engineering, Physics or a related discipline, posess experience in the sensitivity analysis of complex systems, and have familiarity with modelling tecchniques in biomechanics or biomedical engineering. The post is full time for one year, with a starting date of September 1, 2017. The post-holder will report to Dr Pinaki Bhattacharya and Prof Marco Viceconti in the Department of Mechanical Engineering, The University of Sheffield.

Informal inquiries about the job may be sent to Dr Pinaki Bhattacharya (p DOT bhattacharya AT sheffield DOT ac DOT uk)

Click here to apply online. Or search with reference UOS016226.