View Full Version : A course on Bone Cell and Tissue Mechanics

Steve Cowin
01-08-2007, 12:59 AM
A course on Bone Cell and Tissue
Mechanics will be given this year in the week of
July 16-20, 2007 in Udine, Italy at the CISM -
International Centre for Mechanical Sciences-in
the Palazzo del Torso. This course was last given
in 2003 (and before that in 1999, 1995 and 1987).
A description of the course and the names of the
lecturers are given below. In the past the
audience has been as diverse in background as the
lecturers, that is to say spanning the spectrum
from biologists and veterinarians to structural
and biomedical engineers. Contact the CISM for
further information, http://www.cism.it/


Bone mechanics is considered here to
include the mechanical behavior of whole bones as
structural elements, the mechanical behavior of
bone tissue as a material, the response of bone
cells to mechanical and electrokinetic stimuli
and the physiological significance of the
mechanical behavior. Specialists in orthopaedics,
dentistry, biochemistry and molecular and
cellular biology as well as biomechanics are
involved in the bone cell and tissue mechanics.
This topic has only formalized into a distinct
discipline in the last thirty years. During this
period the salient mechanical properties of bone
have been determined, but the salient mechanical
properties of bone cells are only now being

Bone remodeling is the primary research
area in bone mechanics. Bone remodeling is a term
used to describe the renewal and redevelopment of
bone tissue as it adapts to altered load bearing.
That is to say, in the course of time bone
changes its shape, its apparent density, and its
stiffness to adapt to the environmental load it
experiences. In engineering terminology, bone is
an optimum composite and the skeletal system is
an optimal structure. The cellular mechanisms
that constitute the mechanosensory system in bone
tissue and drive the adaptive remodeling are
unknown at the present time, but there are
several promising candidates for the
mechanosensory system.

The subject of bone mechanics is basic to
the design of orthopaedic implanted prostheses
such as artificial hips, knees, finger joints, as
well as dental implants. The engineering design
of these orthopaedic and dental appliances is
less than forty years old and still in a state of
evolution. It is a major manufacturing industry.

The goal of this course will be to review
the entire area of bone cell and tissue
mechanics, with an emphasis on bone remodeling.
Besides being informative, it is hoped that the
course will function as a forum for the exchange
of data, philosophy, and ideas across
disciplinary divides and so provide further
stimulus for a comprehensive approach to the
problems of bone mechanics. We expect an audience
as diverse in background as the lecturers, that
is to say spanning the spectrum from biologists
and veterinarians to structural and biomedical


Professor Stephen C. Cowin
New York Center for Biomedical Engineering
Departments of Biomedical and Mechanical Engineering
The City College of the City University of New York
New York, NY, 10031
+212.799.7970 (Home & Home Fax)
+212.650.5208 (Office)
+212.650.6727 (Office Fax)

Professor John Currey
Department of Biology
University of York
PO Box 373
York, YO10 5YW
44-1904-438589 (Work)
44-1904-633235 (Home)
44-1904-432860 (Fax)

Professor Manuel Doblaré
Professor of Structural Mechanics (Catedratico de M.M.C. y T.E.)
Mechanical Engineering Dept. (Depto. de Ingenieria Mecanica)
University of Zaragoza (Universidad de Zaragoza)
Maria de Luna 3, Campus del Actur, Edificio Agustin de Betancourt
50018 - Zaragoza
Tel. +34-976761912
Fax +34-976762578

Professor Alicia J. El Haj
Institute of Science & Technology in Medicine
Keele University Medical School
Hartshill Campus
Thornburrow Drive
Stoke-on-Trent. ST4 7QB
Telephone: +44 (0)1782 554605
Fax: +44 (0)1782 717079

Prof.dr.ir. Rik Huiskes
Dept. Biomedical Engineering
Eindhoven University of Technology
Wh 0.126
P.O. Box 513
5600 MB Eindhoven
The Netherlands
Phone: +31 40 247 2851
Fax: +31 40 244 7355
GSM: +31 6 290 22485

Professor Allen Goodship
Institute of Orthopaedics and Musculoskeletal Science
University College London
Secretary: Jackie Buckland
Tel: +44(0)208 909 5535
Fax: +44(0)208 954 8560

and Professor of Orthopaedic Science
Royal Veterinary College
Secretary: Pamela Williams
Tel: +44(0)1707 666342
Fax: +44(0)1707 666346