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pschneider62
06-06-2007, 04:17 AM
Two PhD Positions in Bioimaging/Biomechanics
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With recent advances in genetics and molecular medicine there is a
strong need for new procedures and technologies to facilitate biological
quantification for structure function assessment in the life sciences,
such as in skeletal research. There, a number of new microstructural
imaging modalities have been put forward allowing phenotypic
quantification with high precision and accuracy in humans and animals,
especially in the mouse. In the Müller Group, new strategies for 3D
approaches for quantitative bioimaging are investigated. Micro-computed
tomography (µCT) is such an approach used to image and quantify bone in
three dimensions (3D) providing isotropic resolutions ranging from a few
millimeters down to one hundred nanometers. Recently, a synchrotron
radiation (SR) based nano-tomography (nanoCT) station has been designed
and implemented at the Swiss Light Source (SLS) of the Paul Scherrer
Institut (PSI) allowing 3D and fully nondestructive access to the
ultrastructure of biological materials.

Within our Laboratory for Structure Function and Genetics (LSFG) we
currently follow three specific aims:

1) Develop new techniques and methods for quantitative phenotyping of
bone, using microCT and nanoCT.

2) Develop and establish high-throughput functional phenomics for
genetic linkage studies dedicated to bone ultrastructure, using nanoCT.

3) Develop and establish image-guided failure assessment (IGFA) for
the investigation of nanoscopic failure behavior of pathologic bone,
using nanoCT.

The Institute for Biomechanics at ETH Zurich is seeking to appoint two
highly motivated PhD candidates pursuing research in one of these areas.
The successful candidates will work within an international and
interdisciplinary team of biologists, computer scientists, engineers and
physicists at ETH and will have the opportunity to collaborate closely
with the SLS at PSI. The applicants should have a recent master degree
in Engineering or Physics. Good skills in both spoken and written
English are mandatory to work in an international, young and dynamic
team. Knowledge in Bioimaging, Signal Processing, Biomechanics and/or
Bioengineering is an advantage, yet not a prerequisite. The position is
available upon August 1st 2007 or upon mutual agreement. Salaries are
highly competitive and are in line with the guidelines of the ETH.

A Curriculum Vitae, a list of two references and all university classes
attended (including grades) as well as a one-page statement of your
background and research interest should be sent to (preferably by email):

Prof. Ralph Müller, Ph.D.
Institute for Biomechanics
ETH Zürich, Moussonstrasse 18, 8092 Zürich, Switzerland
Email: ram@ethz.ch, Web: http://www.biomech.ethz.ch

For further information please contact Philipp Schneider, +41 44 632 45
69, pschneider@ethz.ch.