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Damien Lacroix
07-12-2007, 01:14 AM
Two PhD positions are available in the Biomaterials, Biomechanics and
Tissue Engineering Research Group of the Universitat Politècnica de
Catalunya (Barcelona, Spain). The research group has an extensive
experience in the development of novel biomaterials and computer
simulations to better understand the interaction between surfaces, cell
biology and mechanical stimuli. The selected candidates will integrate
the research line on Biomechanics and Mechanobiology to work on the
development of new numerical tools for the design of biomaterials for
bone tissue engineering. The advertised positions will start
mid-September 2007 and be funded for 4 years. The candidates should have
a degree in Biomedical Engineering, Mechanical Engineering, or Physics.
Previous knowledge on finite element analysis and programming skills are
highly advantageous. Good skills in both spoken and written English are
expected; knowledge of Spanish is beneficial. Candidates should be able
to work both independently and as a member of a team.

Short descriptions of the positions are given below.

PhD 1: Simulation of bone mechanoregulation of rapid prototyped scaffold
The aim of the project is to design and construct scaffolds for bone
tissue engineering using rapid prototyping techniques (Bioplotter).
Geometrical and mechanical design considerations will be accounted for
and a micro finite element model of the scaffold will be developed and
validated against in vitro experiments. A dynamic simulation will be
setup to model cell adhesion, proliferation and differentiation over
time. The extracellular matrix formation will be modelled and validated
by comparison with in vitro experiments.

PhD 2: Development of a multiscale analysis for tissue engineering
The aim of the project is to develop computational tools at multiscale
levels of the mechanical stimuli experience in tissues under
physiological conditions with applications to tissue engineering. The
candidate will develop a multiscale analysis with tissues modelled using
a microporoelastic approach. A multiscale homogenization approach will
be used in a parallel computing environment. This new approach should
bring a better understanding of the real mechanical stimuli sensed by
the cells when these are stimulated in vitro or in vivo.

Applicants should send a CV with a letter of interest and a list of two
referees before 15 August 2007 to:

Dr. Damien Lacroix
damien.lacroix@upc.edu
Tel : +34 934010711

--
Dr. Damien Lacroix
Technical University of Catalonia
Department of Material Sciences
and Metallurgical Engineering
ETSEIB, Diagonal 647
08028 Barcelona
Spain
Tel: +34 934010711
Fax: +34 934016706
Email: damien.lacroix@upc.edu
Web: www.ibecbarcelona.eu

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