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vsansalone32
06-01-2008, 11:26 PM
Dear subscribers,

Applications are called for a PhD candidate who will carry out research
in biomechanics of bone remodelling at University Paris 12, FRANCE.

Please find below details of the offer.
For further details about the studentship, please contact me or visit
our website:
http://www.univ-paris12.fr/lmp/

Best regards,

Vittorio SANSALONE

Laboratoire de Biomécanique et Biomatériaux Ostéo-Articulaires
CNRS UMR 7052 (Laboratoire de Mécanique Physique)
Faculté des Sciences et Technologie
Université Paris 12 - Val de Marne
61, Av. du Général de Gaulle, 94010 Créteil Cedex, FRANCE
Téléphone : +33 1 45 17 15 72
Fax : +33 1 45 17 14 33
E-Mail : vittorio.sansalone@univ-paris12.fr


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PhD studentship
*Growth and remodelling of bone tissue: poromechanical behaviour,
microstructure and biochemical coupling.*

At Laboratory of Osteo-Articular Biomechanics and
Biomaterials, UMR CNRS 7052
Laboratory of Mechanics and Physics
University Paris 12 - Val de Marne (Paris Est)
61, Av. du Général de Gaulle, 94010 Créteil, France

Contacts Salah Naïli Vittorio Sansalone
e-mail naili@univ-paris12.fr vittorio.sansalone@univ-paris12.fr
tel +33 1 45 17 14 45 +33 1 45 17 15 72
fax +33 1 45 17 14 33
web http://www.univ-paris12.fr/lmp/

Deadline Monday, June 30, 2008

Eligibility Students with a proper degree or expecting to obtain it by
December 2008 are eligible.

Salary 20 000 EUR/year plus benefits; extra money available on
condition.

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*Application procedure*
Interested applicants should send their CV by e-mail. Applications will
be accepted also after the deadline, until the position is filled.

*Keywords*
Biomechanics; Bone; Adaptation, Growth & remodelling; Poromechanics;
Microstructure; Coupled multi-physics phenomena; Modelling & simulation.

*Education and skills required*
The candidate is expected to have a solid background in continuum
mechanics (both solid and fluid mechanics). Previous knowledge of
numerical methods (FEM, FDM, etc.) and scientific programming tools
(C++, MatLab, etc.) is required. A keen interest for biomechanics and
life sciences, as well as a penchant for multidisciplinary research are
important assets.

*Description*
This PhD project focuses on the adaptation (growth and remodelling) of
the bone tissue and its microstructure. Both mechanical and biochemical
stimuli shall be considered to understand and predict mesoscopic bone
properties, addressing in particular its poromechanical response. The
general aim is to develop a biomechanical theory where bone is modelled
as a porous medium whose microstructure adapts to the (mechanical and
chemical) environment. The mesoscale properties of the evolving
microstructure shall be obtained by means of suitable homogenization
procedures. This will eventually lead to an effective macroscopic
characterization of the poromechanical response of bone tissue. Of
necessity, this research shall be multidisciplinary, since the coupling
between mechanics, biology and chemistry will be its main theme. While
doing most of his/her work in mechanics, the student will be asked to
study also topics from biology and chemistry, under the guidance and in
collaboration with experts in these disciplines. The biomechanical model
shall be implemented in a computational code. Results from numerical
simulations shall be eventually compared with experimental outcomes, in
order to validate the model. This research work should provide us with a
better understanding of adaptivity of bone tissue. Ultimately, it could
lead to improvements on the existing therapeutic protocols and clinical
practices.

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