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vsansalone32
07-15-2008, 10:06 PM
Dear Biomch-L Subscribers,

A PhD position is open in our group in the field of bone biomechanics.
Please, forward this call to any person who might be interested.

Best regards,

Vittorio SANSALONE

Laboratoire de Biomécanique et Biomatériaux Ostéo-Articulaires
CNRS UMR 7052 (Laboratoire de Mécanique Physique)
Faculté des Sciences et Technologie
Université Paris 12 - Val de Marne
61, Av. du Général de Gaulle, 94010 Créteil Cedex, France
Téléphone : +33 1 45 17 15 72
Fax : +33 1 45 17 14 33
E-Mail : vittorio.sansalone@univ-paris12.fr

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* PhD studentship *
Growth and remodelling of bone tissue: poromechanical behaviour,
microstructure and biochemical coupling.

* Location *
Laboratory of Osteo-Articular Biomechanics and Biomaterials, UMR CNRS 7052
Laboratory of Mechanics and Physics (http://www.univ-paris12.fr/lmp/)
University Paris 12 - Val de Marne (Paris Est)
61, Av. du Général de Gaulle, 94010 Créteil, France

* Contacts *
Salah Naili, naili@univ-paris12.fr, tel: +33 1 45 17 14 45
Vittorio Sansalone, vittorio.sansalone@univ-paris12.fr, tel: +33 1 45 17 15 72

* Deadline *
Thursday, July 31, 2008

* Eligibility *
Students with a proper degree or expecting to obtain it by December 2008 are
eligible.

* Salary *
20 000 EUR/year plus benefits; extra money available on condition.

* Application procedure *
Interested applicants should send their CV by e-mail. Applications will be
accepted also after the deadline, until the position is filled.

* Keywords *
Biomechanics; Bone; Adaptation, Growth & remodelling; Poromechanics;
Microstructure; Coupled multi-physics phenomena; Modelling & simulation.

* Education and skills required *
The candidate is expected to have a solid background in continuum mechanics
(both solid and fluid mechanics). Previous knowledge of numerical methods
(FEM, FDM, etc.) and scientific programming tools (C++, MatLab, etc.) is
required. A keen interest for biomechanics and life sciences, as well as a
penchant for multidisciplinary research are important assets.

* Description *
This PhD project focuses on the adaptation (growth and remodelling) of the
bone tissue and its microstructure. Both mechanical and biochemical stimuli
shall be considered to understand and predict mesoscopic bone properties,
addressing in particular its poromechanical response. The general aim is to
develop a biomechanical theory where bone is modelled as a porous medium whose
microstructure adapts to the (mechanical and chemical) environment. The
mesoscale properties of the evolving microstructure shall be obtained by means
of suitable homogenization procedures. This will eventually lead to an
effective macroscopic characterization of the poromechanical response of bone
tissue. Of necessity, this research shall be multidisciplinary, since the
coupling between mechanics, biology and chemistry will be its main theme.
While doing most of his/her work in mechanics, the student will be asked to
study also topics from biology and chemistry, under the guidance and in
collaboration with experts in these disciplines. The biomechanical model shall
be implemented in a computational code. Results from numerical simulations
shall be eventually compared with experimental outcomes, in order to validate
the model. This research work should provide us with a better understanding of
adaptivity of bone tissue. Ultimately, it could lead to improvements on the
existing therapeutic protocols and clinical practices.