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Mcgarry, Patrick
08-10-2010, 09:31 PM
Fully Funded Ph.D. Research Position in Biomedical Engineering.

Department of Mechanical and Biomedical Engineering

National Centre for Biomedical Engineering Science (NCBES)

National University of Ireland, Galway (NUIG)



Calling for applicants for a fully funded Ph.D. research position in the field of computational and experimental cell mechanics.



Project title: Mechanical testing and finite element modelling of the response of cells to static and dynamic loading



This Science Foundation Ireland (SFI) funded project involves the investigation of the active response of cells to mechanical stimuli. A mechanical testing apparatus will be constructed to apply static and dynamic loading conditions on cells seeded on 2D membranes and 3D scaffolds. Passive and active forces will be measured in addition to monitoring the remodelling of sub-cellular structures. Experimental data will be analysed using an advanced finite element simulations, where active mechano-sensitive cellular mechanisms are modelled using novel constitutive frameworks. The biomechanics of bond rupture between cells and substrates will also be modelled, as will deformation of the cell nucleus. A link will be established between cell deformation, cell adhesion and gene expression.



The successful applicant will work as part of a dynamic research team in a collaborative environment. Project collaborators: Network of Excellence for Functional Biomaterials (NFB, NUIG); Regenerative Medicine Institute (REMEDI, NUIG); Nanoscale Function Group (Conway Institute, University College Dublin).



Requirements: Applicants should hold a 1.1 or 2.1 honours degree in mechanical or biomedical engineering or a related discipline. The applicant should have a strong background in engineering design and structural analysis. Knowledge of finite element software, CAD softwore, Labview and Matlab would be an advantage. Prior experience in cell and tissue culture, while advantageous, is not mandatory.



Funding: The successful applicant will receive a scholarship of €15-18k per annum for four years plus full payment of Ph.D. fees.



Start date: September-October 2010



For further information please contact:

patrick.mcgarry@nuigalway.ie

(Tel. +353 91 493165)



To apply for this position please send a CV to patrick.mcgarry@nuigalway.ie