View Full Version : NIH/NLoM Visible Human Project

Herman J. Woltring
03-30-1991, 07:12 AM
Dear Biomch-L readers,

While browsing through the NIH Funding database mentioned some days ago, I
came across the following item. I'd be grateful for any comments posted or
emailed on this fascinating project.

Regards -- Herman J. Woltring, Eindhoven/NL
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Date: Wed, 20 Jun 90 12:39:31 EDT
Sender: NIH Guide Primary Distribution
Subject: From NIH GUIDE - Vol. 19, No. 23, June 22, 1990




P.T. 34; K.W. 1004004, 1004005, 0705000, 0706030

National Library of Medicine

The National Library of Medicine (NLM) is undertaking a project to build a
digital image library of volumetric data representing a complete normal adult
human male and female. This "Visible Human Project" will include digital
images derived from photographic images from cryosectioning, computerized
tomography, and magnetic resonance imaging of cadavers. This project is
viewed as a cornerstone for a future set of related image libraries and a test
platform for developing methods and standards.

Technologies underlying computer-based representation and display of complex
three-dimensional biological structure are sufficiently mature that the NLM
can proceed with building prototype digital image libraries. The NLM's Long
Range Planning effort of 1985-86 foresaw a coming era where the NLM's biblio-
graphic and factual database services would be complemented by libraries of
digital images, distributed over high-speed computer networks and by high-
capacity physical media. The NLM Planning Panel on Electronic Imaging was
convened to recommend when and how the NLM might proceed in the development
of such digital image libraries. Much of our understanding of complicated
processes of health and disease lies in images, pictures of body systems,
organs, and molecules which cannot effectively be described in words.

This project will be implemented in three phases:

Phase 1 Acquisition of cadavers, CT and MRI data sets, and selection of a
"typical" male and female cadaver for Stages 2 and 3

Phase 2 Acquisition of anatomy data set from either male or female cadaver

Phase 3 Acquisition of anatomy data set from remaining female or male cadaver

The major technical risks associated with this project will be the selection
of the two cadavers which will prove to be appropriate for use in Phase 2 and
Phase 3; and the techniques of tissue sectioning and image capture sufficient
to obtain the required results. The Ad Hoc Technical Evaluation Committee
will provide oversight at the transition points between phases 1 and 2 and
between phases 2 and 3.

The contractor will be evaluated by the Ad Hoc Technical Evaluation Committee
after the completion of Phase 1. Such evaluation may be on the basis of the
contractor's Phase 1 report, by presentation to the committee or by site visit
to the contractor's site by committee members.

RFP NLM-90-114/SLC will be available in late June 1990, and proposals will be
due 30 days thereafter. Copies of the Request for Proposals may be obtained
by written request only to:

National Library of Medicine
Office of Acquisitions Management
8600 Rockville Pike
Building 38A, Room B1N17
Bethesda, MD 20894
Attention: Sharon Cummings
Telephone: (301) 496-6546