View Full Version : Muscle Fatigue

Roger Enoka
12-27-1995, 03:46 AM
I have been asked to post the following memo on biomch-l as a service to
interested subscribers. Please note that I receive no financial gain relate=
to this announcement. =20

DATE: December 21, 1995


TO: Attendees, International Conference on Neural and
Neuromuscular Aspects of Muscle Fatigue, Miami, FL,
Nov. 10-13, 1994.

=46ROM: Doug Stuart, Conference Chair and for the other
organizers (Simon Gandevia, Roger Enoka, Alan
McComas and Christine Thomas-Local Coordinator).

RE: Availability of a new research monograph on muscle
fatigue at a reduced (bulk-order) price.

Greetings from Tucson! Many of the speakers and discussants
and chairs at our 1994 fatigue conference have participated
in the publication of a new research monograph, Fatigue:
Neural and Muscular Mechanisms, with the conference
organizers as editors. This monograph was published by the
Plenum Publishing Corporation in November, 1995. Its retail
price is $US125. There are no royalties for the editors
and other authors. A copy of the table of contents is

As promised in our 1994 Miami Conference Proceedings, this
volume is being made available to conference attendees at a
reduced price ($US57; including postage cost) provided you
do the following two things by January 31, 1996. Please note
that you may order as many copies as you like.

1. Make out your payment check or money order in US dollars to "The=
of Arizona - Acct No 235040", and mail to Dr. Douglas Stuart, Department of
Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724, US=
Please insure that it will arrive in Tucson no later than January 31, 1996.

2. Immediately E-mail (DGStuart@Mail.Arizona.Edu) or fax
(520-626-2383) Dr. Stuart:
2.1 Confirm or revise your regular mail address, as it appeared in the=
Proceedings of the 1994 Miami conference.
2.2 Affirm that you have sent me your payment under separate cover.

On February 15, 1996, I will send Plenum the bulk-order payment and updated =
address labels, and your book(s) will be mailed to you by Plenum shortly=20

If you were the author or co-author of a chapter in the volume, please note =
in a separate mailing, primary authors will shortly receive a complimentary =
from Plenum, as will senior co-authors who attended the Miami conference. =
However, we assume that all this group will appreciate the opportunity to=20
purchase additional copies at the reduced bulk-order price.

The editors believe that the 505-page book, which addresses issues from the=
forebrain to the contractile proteins, is of the highest quality and, as=
is a fitting tribute to Brenda Bigland-Ritchie. It has 2 prologue and 37=20
subsequent chapters. In all ways, we believe you will be proud to own
the book and will find it of particular value as both a source of reference=
an inspiration for lectures, trainee review sessions, and research on muscle=
fatigue. Furthermore, your departmental/institutional library is sure
to appreciate your inclusion of a copy for their unit. Similarly, you=
have colleagues who would like to be included in your personal component of=
bulk order. They may be included under their own names, or under your name.

Although there will be no post-symposium volume as was originally intended,=
summary of the conference, with commentaries and abstracts, will appear as a=
supplement to Muscle & Nerve in either January or February of 1996.

Thank you for your consideration of this information. If further details=
required, please contact me.

Enclosure: Contents of Fatigue: Neural and Muscular
=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3 D=3D=3D=3D=3D=3D=3D=3D=3D=
=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3 D=3D=3D=3D=3D=3D=3D=3D=3D=
Looking Back Brenda Bigland-Ritchie (New Haven)

The Scientific Contributions of Brenda Bigland-Ritchie C.K.
Thomas, R.M. Enoka, S.C. Gandevia, A.J. McComas and D.G.

Section I: Fatigue of Single Muscle Fibers
1. Myofibrillar Fatigue versus Failure of Activation
K.A.P. Edman
2. Mechanisms of Excitation-Contraction Coupling Relevant
to Skeletal Muscle Fatigue D. G. Stephenson, G.D. Lamb,
G.M.M. Stephenson and M.W. Fryer
3. The Role of Intracellular Acidosis in Muscle Fatigue
D.G. Allen, H. Westerblad and J. L=E4nnegren
4. Role of Interstitial Potassium G. Sj=F8gaard and A.J.

Section II: Fatigue at the Neuromuscular Junction
5. Fatigue at the Neuromuscular Junction: Branch Point vs.
Presynaptic vs. Postsynaptic Mechanisms G.C. Sieck and
6. The Role of the Sarcolemma Action Potential in Fatigue
A.J. Fuglevand
7. Single Fiber Electromyography in Studies of
Neuromuscular Function J.V. Trontelj and E. St=E5lberg

Section III: Fatigue of Single Motor Units
8. Intrinsic Properties of Motoneurons: Implications for
Muscle Fatigue A. Sawczuk, R.K. Powers and M.D. Binder
9. Neuromuscular Frequency Coding and Fatigue D. Kernell
10. Human Motor Units Studied by Spike-Triggered Averaging
and Intraneural Motor Axon Stimulation C.K. Thomas
11. Human Units Studied by Intramuscular Microstimulation
J.M. Elek and R. Dengler

Section IV: Metabolic Fatigue Studied with NMR Techniques
12. Bioenergetics and Muscle Cell Types M.J. Kushmerick
13. Metabolic Correlates of Fatigue from Different Types of
Exercise in Man N.K. V=F8llestad
14. Mechanisms of Human Muscle Fatigue: Quantitating the
Contribution of Metabolic Factors and Activation
Impairment R.G. Miller, J.A. Kent-Braun, K.R. Sharma
and M.W. Weiner
15. Emerging Opportunities with NMR L.A. Bertocci

Section V: CNS Issues: The Case for Segmental Motor
16. Variable-Frequency Stimulation Patterns for the
Optimization of Force during Muscle Fatigue: Muscle
Wisdom and the Catch-like Property S.A. Binder-Macleod
17. Overview: Potential Role of Segmental Motor Circuitry in
Muscle Fatigue U. Windhorst and G. Boorman
18. The Fusimotor System: Its Role in Fatigue K-E. Hagbarth
and V.G. Macefield
19. Role of Muscle Afferents in the Inhibition of
Motoneurons During Fatigue S.J. Garland and M.P Kaufman

Section VI: CNS Issues: The Case for Central Fatigue
20. Central Fatigue: Critical Issues, Quantification and
Practical Implications S.C. Gandevia, G.M. Allen and
21. Single-Trial Readiness Potentials and Fatigue D.
Popivanov, A. Mineva and J Dushanova
22. The Senses of Effort and Force During Fatiguing
Contractions L.A. Jones
23. Tryptophan, 5-Hydroxytryptamine and a Possible
Explanation for Central Fatigue E.A. Newsholme and E.

Section VII: Task Dependency of Fatigue Mechanisms
24. The Significance of Motor Unit Variability in Sustaining
Mechanical Output of Muscle A.J. Sargeant and D.A
25. Intramuscular Pressures for Monitoring Different Tasks
and Muscle Conditions O.M. Sejersted and A.R. Hargens
26. Task-Dependent Nature of Fatigue in Single Motor Units
B.R. Botterman
27. Task-Dependent Factors in Fatigue of Human Voluntary
Contractions. B. Bigland-Ritchie, C.L. Rice, S. J.
Garland and M.L. Walsh.

Section VIII: Integrative Systems Issues
28. Fatigue and the Design of the Respiratory System S.L.
Lindstedt and H. Hoppeler
29. An Integrative View of Lmitations to Muscular
Performance J.A. Dempsey and M.A. Babcock
30. Respiratory Muscle Fatigue D.K. McKenzie and F.
31. Fatigue of Jaw Muscles and Speech Mechanisms T.S. Miles
and M.A. Nordstrom

Section IX: Fatigue of Adapted Systems: Overuse, Underuse and
32. Fatigue in Adapted Systems: Overuse and Underuse
Paradigms T. Gordon
33. Associations Between Muscle Soreness, Damage, and
Fatigue P.M. Clarkson and D.J. Newham
34. Muscle Fatigue in Old Animals: Unique Aspects of Fatigue
in Elderly Humans J.A. Faulkner and S.V. Brooks
35. Historical Perspective: A Framework for Interpreting
Pathobiological Ideas on Human Muscle Fatigue R.H.T.
Edwards, V. Toescu and H. Gibson
36. Fatigue Brought on by Malfunction of the Central and
Peripheral Nervous Fystems A.J. McComas, R.G. Miller
and S.C. Gandevia

37. Neurobiology of Muscle Fatigue: Advances and Issues
S.C. Gandevia, R.M. Enoka, A.J. McComas, D.G. Stuart
and C.K.Thomas.

Roger M. Enoka, Ph.D.
Department of Biomedical Engineering/Wb3
Cleveland Clinic Foundation
9500 Euclid Avenue
Cleveland, OH 44195, USA

Phone: 216-444-1805
=46ax: 216-444-9198
E-mail: enoka@bme.ri.ccf.org
URL: http://www.ccf.org/ri/bme/people/enoka/enoka.html