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Stewart, Sandy 301-827-5610
04-06-1998, 10:22 PM
Dear Listmembers:

On March 27 I submitted the following request for information:

> I am looking for normal geometrical dimensions for the inside
> of the left ventricle and left atrium for use in a simple finite
> element model of mitral regurgitation (using FIDAP). I really don't
> need the detail provided by, for example, the gigabytes of data
> contained in the NLM visible human. An axisymmetric elliptical model
> may be good enough for a first effort. However, I would also be
> interested in a fairly detailed 3-d mesh of the inner dimensions of the
> left heart for asymmetric simulation. In the latter case, a data set
> of x,y,z points in some common file format would be useful.

Many thanks to those who responded to my request. An edited
summary of responses follows:

------------------------------------------------------------------------

I have some fairly detailed FEM mesh data for the entire canine heart as
end-diastole and end-systole, including the LV. The data was obtained
from gated MRI. Drop me a line if you are interested.

Michael S. Sacks,Ph.D.
Assistant Professor
Department of Biomedical Engineering
POB 248294
University of Miami
Coral Gables, FL 33124-0621
email: msacks@coeds.eng.miami.edu

------------------------------------------------------------------------

An EXCELLENT source of this information is the Geigy Scientific Tables:
Volume 1. They list all dimensions across many age groups and other
prevailing conditions.

James F. Antaki, PhD
Director, Artificial Heart Research
McGowan Center for Artificial Organ Development
University of Pittsburgh
antaki@pittsurg.nb.upmc.edu

------------------------------------------------------------------------

You should probably check out the work of Dr. Andrew McCulloch at the
University of California - San Diego. He has developed several Finite
Element models of the heart that include actual geometries. Most of his
work has been done using prolate spheriodal coordinates.

Tim S. Smith |
Scientist | Of course any opinions expressed
Computational Chemistry & Biology | or implied are solely mine - Not
Procter & Gamble Pharmaceuticals | that of... You get the idea.
Cincinnati, Ohio 45252 |
tssmith@pg.com

------------------------------------------------------------------------

I suggest you contact:
Elliot R. McVeigh
Department of Biomedical Engineering
407 Traylor Building
720 Rutland Avenue
Johns Hopkins School of Medicine
Baltimore, Maryland
21205
Tel 410 502 6958
Fax 955 0549
Sec 502 6959
emcveigh@tempest.bme-mri.jhu.edu
================================================== ================
Peter A. Hardy, Ph.D
Department of Biomedical Engineering
Cleveland Clinic Foundation, Wb3
9500 Euclid Avenue, Cleveland, Ohio
44195
hardy@bme.ri.ccf.org

------------------------------------------------------------------------

Again, many thanks to all who replied.

--Sandy Stewart

************************************************** ***************
* Sandy F.C. Stewart, PhD *
* Hydrodynamics & Acoustics Branch *
* Center for Devices & Radiological Health *
* Food & Drug Administration *
* Rockville, MD 20850 *
* (301) 827-5610 *
* sxs@cdrh.fda.gov *
************************************************** ***************