Thank you very much to everyone who responded to my optimization in
biomechanics message. The feedback was excellent and very informative.

Hello Everyone,

I am trying to find any information relating the numerous
methods to biomechanics. If anyone has something remotely resembling this,
could you please point me in a direction where I can find it? Your help is
much appreciated.

Best Regards,

Todd G. Langer


Secco Emanuele Lindo
Dip. Informatica e Sistemistica
Università di Pavia
Via Ferrata, 1 - 27100 Pavia - Italia
cell. +39 (0)347
tel. +39 (0)382 50.53.52
fax. +39 (0)382 50.53.73
A good article for optimization principles in the analysis of natural
could be:

Nelson W. L., (1983), ‘Physical Principles for Economies of Skilled
Biol. Cybern., Vol. 46, pp. 135-147

michael schwartz
Here's a good review article:

Inverse Optimization: Functional and Physiological Considerations Related to
the Force-Sharing Problem
Tsirakos T, Baltopoulos V and Bartlett R
Critical Reviews in Biomedical Engineering, 245(4&5):371-407 (1997)

Fullmer Jim
Try Dr. Karim Abdel Malek at University of Iowa's center for computer aided

Brian May
Senior Research Engineer
Clinical and Industrial Technology, Inc.
203 New Chapter Rd.
Seneca, SC 29678
(864) 985-0606
I have delved into optimization of biomechanics previously. Here are the
article I used as guides:

A physiologically based criterion of muscle force prediction in locomotion.
Crowninshield RD and Brand RA. Biomechanics 14 (11) pp793-801. 1981.

Theoretical prediction of muscle forces on the mandible during bite. Kand
QS, Updike DP, and Salathe EP. Transactions of the ASME Vol. 112, pp
432-36. 1990.

Producing physiologically realistic individual muscle force estimations by
imposing constraints when using optimization techniques. Challis JH. Med.
Eng. Phys Vol. 19 (3), pp 253-61.1997

Comparison of muscle forces and joint load from an optimizatin and emg
assisted lumbar spine model: towards development of a hybrid approach.
Cholewicki J, McGill SM, and Norman RW. J. Biomechanics Vol 28 (3), pp
321-31, 1995.

Modelling of forces in the human masticatory system with optimization of the
angulations of the joint loads. Trainor PGS, McLachlan KR, and McCall WD.
Journal of Biomechanics, Vol 28 (7) pp. 829-43, 1995

The application of optimization methods for the calculation of joint and
muscle forces. Barbanel JC. Engineering in Medicine vol 12 (1) pp29-33,

Muscular synergism I: on criteria for load sharing between synergistic
muscles. Dul J, Townsend MA, Shiavi R, and Johnson GE. J. Biomechanics Vol
17 (9), pp 663-73, 1984.

Optimization of muscle-force sequencing in human locomotion. Pedotti, A,
Krishnan VV, and Stark L. Mathematical Biosciences Vol. 38, pp 57-76, 1978.

This list is by no means exhaustive, but is a good start. I recommend
medline searches for optimization.

sylvain grenier
Check out this page. It has a fairly comprehensive summary.

Look for stress optimisation of bone.

Nick Brown
Post Doctoral Fellow
The University of Texas at Austin
There is a considerable body of literature on musculoskeletal modeling for
human biomechanics and you could probably find most of this through Medline.
have included some references below that might get you started as well.

Challis, J. H. (1997). “Producing physiologically realistic individual
force estimations by imposing constraints when using optimization
Medical Engineering and Physics 19(3): 253-261.

Challis, J. H. and D. G. Kerwin (1993). “An analytical examination of muscle
force estimations using optimization techniques.” Journal of Engineering and
Medicine (Proc Instn Mech Engrs) 207: 139-148.

Crowninshield, R. D. (1978). “Use of optimization techniques to predict
forces.” Journal of Biomedical Engineering 100: 88-92.

Crownishield, R. D. and R. A. Brand (1981). “A physiological based
criterion of
muscle force prediction in locomotion.” Journal of Biomechanics 14: 793-801.

Delp, S. L., J. P. Loan, et al. (1990). “An interactive graphics-based
model of
the lower extremity to study orthopaedic surgical procedures.” IEEE
on Biomedical Engineering. 37(8): 757-767.

Garner, B. A. and M. G. Pandy (2000). “Musculoskeletal model of the upper
based on the visual human dataset.” Computer Methods in Biomechanics and
Biomedical Engineering.

Neptune, R. R. and M. L. Hull (2000). “A theoretical analysis of preferred
pedaling rate selection in endurance cycling.” Journal of Biomechanics 33:

Pandy, M. G. and F. C. Anderson (2000). “Dynamic simulation of human
using large-scale models of the body.” Phonetica 57: 219-228.

Pandy, M. G. and F. E. Zajac (1991). “Optimal muscular coordination
for jumping.” Journal of Biomechanics 24: 1-10.

John Rasmussen, Assoc. Prof., PhD,
The AnyBody Group,
Institute of Mechanical Engineering,
Aalborg University, Denmark
The AnyBody project deals with simulation of human motion by means of
so-called inverse-inverse dynamics. We employ an optimization technique to
distribute the forces between redundant muscles, and we employ another
optimization technique to indentify the motion.

You can read much more about the method in the list of publications (many
available for download) on our homepage,

Hamid Katoozian, Ph.D
The Center for Locomotion Studies (CELOS)
Pennsylvania State University
29 Recreation Building
University Park, PA 16802-5702
Tel: (814) 865-1972
(814) 863-0993
Fax: (814) 863-4755
I've done some work in this field, take a look at the following:

1.Katoozian H, Davy D. "Effects of Loading Conditions and Objective Function
on Three-Dimensional Shape Optimization of Femoral Component of Hip
Endoprosthesis", 2000, Med.Eng.&Phys. 22;pp.243-251.

2.Katoozian H, Broom N, Robertson P. "Poroelastic Parameter Estimation of
Intervertebral Disc: A Finite Element and Evolutionary Based Algorithm",
American Society of Biomechanics meeting, July 2000, Chicago, IL, USA.

3.Katoozian H, "A Finite Element Based Distributed Parameters Approach to
the Identification of Structural Characteristics of Bone", Proceedings of
International Society of Biomechanics, August 1999, Calgary, Canada, ISB
Proceedings Book p.848.

4.Katoozian H, Arshi A, Saadati Y. "Optimal Design of Fiber Reinforced
Composite Materials for Femoral Component of a Total Hip Endoprosthesis",
Proceedings of International Society of Biomechanics, August 1999, Calgary,
Canada, ISB Proceedings Book p.179.

5.Katoozian H. "Analysis of Certain Inverse Problems in Biomechanics Using
Nonlinear Optimization and Boundary Element Method", 16th Congress of
International Society of Biomechanics, August 1997, Tokyo, Japan. ISB
Proceedings Book p.25.

6.Nicollella D, Wu Y, Katoozian H, Davy D. "A Probabilistic Analysis of the
Structural Response of a Cemented Hip Implant", ASME Bioengineering Summer
Conference, June 1997, Sun River, Oregon, USA.

8.Katoozian H, Davy D. "Effects of Objective Function on Outcomes in Femoral
Stem Shape Optimization for Total Hip Replacement", Second World Congress of
Biomechanics, June 1994, Amsterdam, The Netherlands.

9.Davy D, Katoozian H. "Three-Dimensional Shape Optimization of Femoral
Components of Hip Prostheses with Frictional Interface", Transactions 40th
Orthopaedic Research Society, 1994, Vol 19, p.223.

10.Katoozian H, Davy D. "Three-Dimensional Shape Optimization of Femoral
Components of Total Hip Prostheses", ASME/ASCE/AIChe Bioengineering,
ASME/BED, 1993, Vol 24, pp.552-555.

Katrin Elbert, Ph.D.
Dr. Don Bartel at Cornell University has done work in optimization (while I
was his student there, he even taught a class in this). You may want to
contact him regarding your specific questions.

Helio Schechtman, PhD
Programa de Computacao Cientifica
Fundacao Oswaldo Cruz
Av. Brasil 4365, Residencia Oficial
21045-900, Rio de Janeiro, RJ
Phone: (+55 21) 598 43 69; 598 43 99; 573 02 91; 573 61 93
FAX: (+55 21) 270 51 41
There were some very good papers on the subject on the 70 - 80's. Try Seireg
and Arvirkar.

Dr. Cheryl Riegger-Krugh
I think Scott Delp has done work here

Todd G. Langer
Graduate Research Engineer
Rocky Mountain Musculoskeletal
Research Laboratory
2425 S. Colorado Blvd. Suite 280
Denver, CO 80231
Fax: (303)759-2316

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