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NYC Bone Seminar 10/24 on Bone Microstructure

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  • NYC Bone Seminar 10/24 on Bone Microstructure

    To Bone Researchers in the NYC area:
    The NYC mineralized tissue seminar will have its second
    seminar in its new millennium series on Wednesday night this week
    November 7th. The speaker is Haviva M. Goldman, Ph.D. Assistant
    Professor of Anthropology and Archaeology at the Brooklyn College,
    CUNY. She will speak on THE SIGNIFICANCE OF HETEROGENEITY IN THE
    MICROSTRUCTURAL AND GEOMETRIC PROPERTIES OF HUMAN BONE. An abstract
    of this talk and a description of her research interests are given
    below. The same information on the other fall seminar speakers is
    posted on www.bonenet.net and will be circulated as the date of each
    seminar approaches.

    Speaker: Haviva M. Goldman, Ph.D. Assistant Professor of Anthropology
    and Archaeology at the Brooklyn College, CUNY

    Title: THE SIGNIFICANCE OF HETEROGENEITY IN THE MICROSTRUCTURAL AND
    GEOMETRIC PROPERTIES OF HUMAN BONE

    Abstract: Despite extensive research into the effects of aging on
    bone tissue properties, gaps remain in our knowledge of the causes
    and extent of heterogeneity in the material (i.e. histological
    composition) and structural (i.e. geometric shape) properties of
    bone. As such information is important both for elucidating the
    relationship between bone structure and its functional adaptation,
    and for understanding the etiology of age-related diseases such as
    osteoporosis, a detailed study documenting this variability within
    the mid-shaft femur of a large, well-documented autopsy sample was
    undertaken.
    Collagen fiber orientation and mineralization density are two aspects
    of a bone's microstructure that are known to influence the mechanical
    properties of bone. Although their spatial distributions have been
    hypothesized to reflect loading during life, their variability within
    an adult sample is relatively unknown. Using circularly polarized
    light and backscattered electron microscopy it was possible to obtain
    images of entire femoral cross-sections that could be examined with
    respect to these two variables. By also calculating measures of
    cross-sectional geometry, it was possible to provide information
    about the regularity of bending loads at the femoral mid-shaft that
    could be examined relative to the microstructural organization.
    Extensive variability characterized each of these properties, such
    that it was not possible to identify a single pattern of
    microstructural organization for the human mid-shaft femur, even
    within a single age or sex group. In addition, despite an average
    coincidence between microstructural organization and predicted
    bending forces at the mid-shaft, the vast majority of individuals in
    this sample show no relationship among these variables. These
    results indicate that these variables act somewhat independently,
    resulting in different optimal configurations that may reflect an
    individual's unique life history. The implications of these results
    for studies of human bone biology are discussed from both an
    anthropological and biomechanical perspective.

    RESEARCH INTERESTS OF HAVIVA GOLDMAN: Haviva recently completed her
    doctorate in Anthropology through the CUNY Graduate Center (as part
    of the New York Consortium of Evolutionary Primatology (NYCEP)
    Graduate Program in Anthropology). Her dissertation research focused
    on intra-population variability in microstructural and geometric
    properties of the human mid-shaft femur with age and sex. The
    project stemmed from an interest in applying histological research to
    studies of functional adaptation of past (archaeological and fossil)
    human populations and in better understanding the processes of human
    variability in skeletal aging. She will continue to pursue her
    interests in bone biology, extending her research to include a
    variety of modern and archaeological human population samples, as
    well as addressing issues of growth and development by studying
    variability in bone microstructure in juvenile bone as well.

    NOTE: PRIOR TO HAVIVA GOLDMAN'S SEMINAR THERE WILL BE A SHORT
    PRESENTATION TO PROFESSOR MELVIN MOSS OF COLUMBIA P & S IN
    RECOGNITION AND APPRECIATION FOR HIS BEING THE CREATIVE SPIRIT AND
    EFFORT DRIVING THE PUBLIC SEMINAR SERIES ON MINERALIZED TISSUE
    RESEARCH (THE BONE AND TOOTH CLUB) IN TRANSITIONAL YEARS.

    WHERE AND WHEN: The seminar series is to be held this Fall in room
    3309 at the City University of New York (CUNY) Graduate Center (GC)
    on Wednesdays from 7 to 8:30 PM. There will be some socializing
    before the seminar in the GC snack bar on the first floor, the 365
    Express.

    TRAVEL TO THE CITY UNIVERSITY OF NEW YORK (CUNY) GRADUATE CENTER (GC)

    The Graduate Center (GC) of the City University of New York
    (CUNY) is located in the newly renovated Altman Building at 365 5th
    Avenue. The Altman Building occupies a city block bounded by 35th and
    34th street on the north and south, respectively, and by Madison
    Avenue and 5th Avenue and on the east and west, respectively. The
    Altman Building is catty-corner from the Empire State Building. The
    GC shares this building with the Science Division of the New York
    Public Library and Oxford University Press. The entrance to the GC is
    on 5th Avenue between, and almost equidistant from, East 34th Street
    and East 35th Street.

    The Pennsylvania Station (Amtrak, LLRR and New Jersey
    Transit) is between 31st street and 33rd street on 7th Avenue. Grand
    Central Station (Metro North) is on 42nd Street at Park Avenue. Park
    Avenue is two blocks east of 5th Avenue (Madison is in between). Both
    of these main line stations are short walks from the GC. The PATH
    trains to New Jersey have a station at 34th Street and 6th Avenue.
    There is also a heliport at 34th Street and East river, 6 avenue
    blocks to the east.

    Almost all the Manhattan subway lines have a station on 34th
    Street and within several avenue blocks of the GC. There are a number
    of bus lines that run on 34th street and on 5th Avenue. There are a
    number of parking garages around the GC. There is money to support
    parking for interested students, apply to Steve Cowin
    (scccc@cunyvm.cuny,edu).

    THE LOCATION OF THE BONE SEMINAR ACTIVITIES WITHIN THE GRADUATE CENTER (GC)

    When you enter the GC from 5th Avenue there is a reception
    counter in the center of a reception room and the elevators are
    straight ahead. If you arrive at the GC with a few minutes to spare
    before 7 PM you should consider stopping at the 365 Express on the
    1st floor for sandwiches, snacks and drinks and to socialize with the
    other seminar attendees and the evening's speaker. The 365 Express is
    directly off the GC reception room on the 1st floor (the room you
    entered from the street), off the southeast corner of the room. The
    seminar room is on the 3rd floor (#3309) and accessable by elevator.
    Before you are allowed to walk down the hall to the bank of elevators
    you must identify yourself to the security people. This can be done
    with a CUNY ID or a picture ID (and your signature in a guest book).
    When you get off the elevator on the 3rd floor you head east, then
    north, then east again to arrive at room 3309.

    CLOSING NOTES

    Future seminars are posted on www.bonenet.net, a website dedicated to
    research on the mechanosensory system in bone. (This website is
    operational, but not fully developed and suggestions for further
    development of the site would be appreciated.) You may request a
    reminder for each seminar by sending an email to Steve Cowin
    (scccc@cunyvm.cuny.edu).

    We will welcome your attendance and hope that you will pass along
    this information to interested colleagues. Please direct your
    questions, requests for more information and feedback to me.

    Kind regards, Steve Cowin
    --

    ************************************
    Phone (212) 799-7970 (Office at Home)
    Fax (212) 799-7970 (Office at Home)
    Please note that my old fax number at home [(212) 787-3757] is no
    longer active.
    Phone (212) 650-5208 (Work)
    Email


    IMPORTANT, PLEASE NOTE
    NEW (2001) PREFERRED MAILING ADDRESS
    Stephen C. Cowin
    2166 Broadway
    Apartment 12D
    New York, NY 10024

    The phone number and zip code are unchanged.

    WORK ADDRESS:
    Stephen C. Cowin
    Director, New York Center for Biomedical Engineering
    School of Engineering
    The City College
    138th Street and Convent Avenue
    New York, NY 10031-9198, U. S. A.
    *************************************

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