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  • basic question on image analysis of CT scans

    Hello to the group,

    The research group at Children's Hospital - San Diego has recently begun
    collaborative work with local universities in the area of finite element
    modeling. We wish to use CT scans of femurs from normal and pathological
    patients. As one of the inputs to the patient specific FE model, we need to
    apply trabecular patterns from the scans. We have discussed using basic
    image analysis software to determine density, alignment and angulation of
    the trabeculae. However, this is an entirely new application for us and we
    are a bit mystified on what software/packages exist to handle such
    requirements. I have had little success reviewing the literature and
    accessing biomch-l to determine potential solutions. My questions (simply
    put) are:

    (1) What previous techniques have people used to determine
    alignment/angulation/density of trabecular bone from CT scans?

    (2) Perhaps qualitatively, what has been the success of using such
    techniques?

    (3) How laborious is this image analysis task?

    I appreciate all inputs and will post a summary.

    By the by, the summary to my question on application of strain gages to
    spinal screws will follow next week.


    Regards,

    Andrew



    Andrew Mahar, MS
    Orthopedic Biomechanics Research Center

    Children's Hospital - San Diego
    MC5054
    3020 Children's Way
    San Diego, CA
    92123-4282
    P: 858-495-4975 "I drank what???"
    F: 858-614-7494 -Last words of Socrates
    amahar@chsd.org

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