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Osteoporotic Bone Properties

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  • Osteoporotic Bone Properties

    Thanks to all of you who responded to my post on Osteoporosis.
    Here is a summary of the replies I received.
    You'll find very little published data on the mechano-physical properties of
    osteoporotic bone. In our lab we have been collecting baseline data on the
    pphysical properties of normal and pathological bone (cortical) for more
    than ten years. Do a medline search on the work of SIDNEY LEES and you
    should come up with a number of references to get you started. I am currently
    doing work on the relationship between physical properties (i.e. density,
    longitudinal elastic modulus, equatorial diffraction spacing) and
    structural properties in growing bone. Several publications should be coming
    out within the next year or so.

    Douglas B. Hanson, Ph.D.
    Bioengineering Department
    Forsyth Dentla Center
    140 Fenway
    Boston, MA 02115


    Look up references in Journal of Biomechanics for bone. That should
    give you most of the elastic properties. I do not think much, if
    anything, has been done on the viscoelastic properties of bone,
    no less osteoporotic. Contact Barbara Boyen at UT (next door)
    as she is a bone person.

    Hospital for Special Surgery
    [Peter Torzilli]
    Jonathan Dingwell wrote: (

    If you have acces to Medline, try doing an author search on the following peo-
    All of them have done fairly extensive work in the area of strength properties
    and osteoporosis in bone, as well as the structural changes which occur
    in osteoporosis (which in turn will inherently effect the material properties
    of cancellous bone as a whole).
    A. M. Parfitt
    A. Vesterby
    Li. Mosekilde
    J. S. Arnold
    H. J. G. Gunderson
    N. J. Garrahan
    M. Kleerekoper

    The following specific references may also be of use:

    Pugh, J.W., Rose, R.M., and Radin, E.L., 1973, "Elastic and Viscoelastic
    Properties of Trabecular Bone", J. Biomechanics, v. 6, pp. 475 - 485

    Weaver, J.K., and Chalmers, J., 1966, "Cancellous Bone: its Strength and
    Changes with Aging...", J. Bone and Joint Surgery, v. 48A, pp. 289 - 298

    Gibson, L. J., 1985, J. Biomechanics v. 18, pp. 317 - 328

    _Mechanical Properties of Bone_ {book}, by F. Gaynor Evans
    1973, Charles C. Thomas, Springfield, Ill.

    Dear Daniel,
    In the Yearbook of Physical Anthropology 33:151-194(1990) there is
    probably some help for you i.e. 43 pages review about osteoporosis
    by Stini,W.A.
    including 1 table about mineral content and density. In the reference
    list there are some papers about mechanical properties related to
    osteoporosis. At least I found one on the first page
    about 'predicting femoral neck strength from bone mineral data'
    Maybe there are more and maybe the paper is useful for you.
    A second paper from Galloway,Stini and Fox there are more tables
    but concerning mostly the loss in height. The list of references
    of this paper maybe useful. The title is 'Stature loss among older uni-
    ted states populations and its relation to bone mineral status'
    in American Journal of Physical Anthropology 83(1990)467-476
    Johan Molenbroek
    Delft University of Technology