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PhD assistantship available

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  • PhD assistantship available

    A graduate student fellowship is available beginning the 2003-2004 academic
    year to study knee biomechanics. The primary focus of our research group
    is to understand how mechanical signals are transduced in the meniscus. The
    research will involve the creation of a microstructural finite element
    model of the knee joint. The results of the theoretical FEM will be used
    as input for a biological models to study the biochemical signaling
    pathways in menisci following exposure to mechanical stimuli. This will
    involve the stimulation of meniscal cells in vitro using a parallel plate
    flow chamber and compression of meniscal explants to quantifying
    intracellular signaling mechanisms such as cytosolic calcium oscillations,
    and gene and protein expression. Both experimental and computational
    approaches will be used to study the response of menisci to mechanical
    stimulation to understand diseases like osteoarthritis.

    Michigan Technological University is located in Michigan's Upper Peninsula.
    The community offers a small-town environment with outstanding four-season
    recreational opportunities.

    Applicants should have a B.S. or M.S. in Mechanical Engineering, Biomedical
    Engineering, or a closely related field. Prior work in finite element
    modeling and theoretical mechanics is helpful. Send a statement of interest
    and a resume or CV to:


    Tammy Haut Donahue
    Department of Mechanical Engineering
    Michigan Technological University
    1400 Townsend Dr.
    Houghton, MI 49931

    thdonahu@mtu.edu
    www.me.mtu.edu/~thdonahu
    voice (906)487-2078
    fax (906)487-2822

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