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NYC Bone Seminar on Tuesday,October 26th: Tim Bromage of the New York University College ofDentistry,who will speak on " Lucy falls from sky and returns lostdiamonds! Confocal Circularly Polarized light Microscopy of theEarly Hominid Skeleton."

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  • NYC Bone Seminar on Tuesday,October 26th: Tim Bromage of the New York University College ofDentistry,who will speak on " Lucy falls from sky and returns lostdiamonds! Confocal Circularly Polarized light Microscopy of theEarly Hominid Skeleton."

    Dear colleagues and students:

    The second seminar in the Fall 2004 Bone Seminar Series will be on
    Tuesday October 26 with a presentation by Tim Bromage of the New York
    University College of Dentistry, who will speak on " Lucy falls from
    sky and returns lost diamonds! Confocal Circularly Polarized light
    Microscopy of the Early Hominid Skeleton."

    Details of all seminars appear on our website: http://bonenet.net/index.html
    Details of this seminar appears below.

    I would greatly appreciate in any person interested in the Bone
    Seminar Series, the Bone Fluid Flow Workshops or the BoneNet.net
    website http://bonenet.net, filling out a questionnaire to help me
    prepare the annual report to the National Science Foundation, which
    supports these activities. The questionnaire is also downloadable at
    http://bonenet.net/questionnaire_0409.pdf.

    Many thanks, Steve Cowin

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    October 26, 2004 Seminar

    SPEAKER: Timothy G. Bromage, PhD, Department of Biomaterials, New
    York University College of Dentistry

    TOPIC: Lucy falls from sky and returns lost diamonds! Confocal
    Circularly Polarized light Microscopy of the Early Hominid Skeleton

    PLACE AND TIME: Room 9207, CUNY Graduate Center, 7:00 PM

    ABSTRACT: Skeletal microanatomy is typically investigated by some
    form of light microscopy on specially prepared samples, such as
    histological thin sections, or by scanning electron microscopy (SEM)
    of bulk specimens. However, unique African early hominid remains
    from Pliocene localities some 2-4 million years old are not readily
    available for histological sectioning, and bulk examination by SEM is
    restricted to first surfaces. A practical alternative is confocal
    scanning optical microscopy (CSOM). This permits "optical
    sectioning" upon and below the intact surfaces of opaque materials,
    which generates excellent reflection images and provides basic
    details of bone and tooth histological microanatomy equal to that
    produced by conventional research microscopes. This is all very
    well, but African early hominid repositories do not have available
    CSOM technologies, requiring that we bring such an instrument to the
    fossils. This has prompted development of the first portable CSOM,
    the prototype of which has recently been taken to Ethiopia, Kenya,
    and South Africa for its first glimpse of the hard tissue
    microanatomy of Australopithecus, Paranthropus, and early Homo
    species. CSOM imaging of the dentition is demonstrating
    species-specific variations of enamel structure related to functional
    and life history adaptations. Further, because the portable CSOM is
    configured to generate reflected circularly polarized light images,
    we are able to study and analyze preferential collagen fiber
    orientations in bone tissue and thus skeletal function in our fossil
    ancestors.

    RESEARCH INTERESTS of Tim Bromage: Comparative hard tissue biology
    and microanatomy in relation to functional, life history, and
    environmental reconstruction; human evolution; development of
    practical solutions to technical problems of mineralized tissue
    specimen preparation and imaging.

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    Questions and Feedback Contact

    Stephen C. Cowin PhD
    New York Center for Biomedical Engineering
    Departments of Biomedical and Mechanical Engineering
    School of Engineering
    The City College of New York
    138th Street and Convent Avenue
    New York, NY 10031-9198, USA

    Phone:
    (212) 799-7970 (Office at Home)
    (212) 650-5208 (Office at Work)

    Fax:
    (212) 799-7970 (Office at Home)

    Email:
    scowin@earthlink.net


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