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Soft skeletal tissue differentiation : mechanical properties ofmultiponent mesenchymal

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  • Soft skeletal tissue differentiation : mechanical properties ofmultiponent mesenchymal

    Dear members

    In spite of the weak potential of spontaneous repairing of cartilaginous
    tissues, it is possible to initiate, in vivo as well as in vitro, mesenchymal
    tissue regeneration, involving progenitor cells. This process recapitulate some
    cellular event of embryonic skeletal formation. The material properties of
    multiponent mesenchymal tissue change during the differentiation process
    associated with skeletal regeneration. [Loboa E.G. et al., 2003] have developed
    a mathematical approach for describing time dependent material property changes
    during the formation of cartilage, fibrocartilage and fibrous tissue.
    Mechanical properties of articular cartilage, fibrocartilage and fibrous
    tissues can be found in the literature but I donít have information about the
    mechanical properties of multiponent mesenchymal tissue. I donít find
    experimental studies which determined values for differentiating multipotent
    mesenchymal tissue.

    I'd appreciate your suggestions and will post a summary of replies in due

    Kind regards

    ************************************************** *******************
    Martine Pithioux CR-CNRS
    Laboratoire d'Aerodynamique et de Biomecanique du Mouvement
    Laboratory of Aerodynamics and Biomechanics of Motion
    LABM - USR 2164 CNRS/Universite de la Mediterranee
    163, Avenue de Luminy, Case Postale 918
    13288 MARSEILLE Cedex 09, FRANCE
    Tel: +33(0)-4-91-26-61-77
    Tel Stand: +33(0)-4-91-26-60-30
    Fax: +33(0)-4-91-41-16-91

    ************************************************** *******************

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