Dear Biomch-L readers,

The software described in the following announcement may be

useful for biomechanical studies. Most of us are familiar

(unfortunately) with the situation where statistical analysis

could not provide a good answer to the research question. This

software helps you to prevent such problems by considering

statistical analysis in the planning stage. The software is in

the public domain. I have not tried this, so comments are

welcome.

-- Ton van den Bogert, Biomch-L moderator

>From: bwb@odin.mda.uth.tmc.edu (Barry W. Brown)

>Newsgroups: comp.lang.fortran,sci.math.num-analysis,sci.math.stat,sci.stat.math,comp.programm ing,sci.stat.consult

>Subject: ANNOUNCE - Sample Size, Power, Etc. Program

>Date: 9 Nov 1993 15:49:34 GMT

>Organization: University of Texas M.D. Anderson Cancer Center

STPLAN 4.0

STPLAN performs power, sample size, and related calculations needed to

plan studies. Parameters of a test include those necessary to

describe the distributions under the null and alternative hypotheses,

sample sizes, significance levels, and power. Given values for all

but one parameter, STPLAN will calculate the value of that one

parameter.

The following testing situations are covered by STPLAN:

Studies with Outcomes Distributed According to the Binomial Distribution

One-sample test

Two-sample test

Two-sample above and below the median

Fisher's exact

Matched pairs test for equality of proportions

Conservative versus expensive treatment

Two-sample test in which one group is a historic control

K-sample

Case-control

Sample size correction for loss of subjects over time

Studies with Outcomes Distributed According to the Poisson Distribution

One-sample test

Two-sample test

Studies with Outcomes Distributed According to the Normal Distribution

One-sample test

Two-sample test, equal variances

Two-sample test, unequal variances

Two-sample log-normal

Studies with Outcomes Distributed According to the Exponential Distribution

One-sample test

Two-sample test

Studies whose Outcome is a Set of Survival Times.

Randomized clinical trial for exponential survival times

Comparison with a historic control - exponential survival

Randomized clinical trial - two different hazard rates depending on time

Studies whose Outcome is the Correlation Coefficient

One-sample test

MAJOR CHANGES IN 4.0

The major changes are: (1) the ability to produce tables of any one

quantity as a function of any other, and (2) a complete report format

that allows exact reconstruction of the calculation. In addition

three new testing calculations have been added.

A TASTE OF THE OUTPUT OF THE NEW VERSION

***** Two-sample Binomial (Arcsin approximation) *****

These calculations are for a two sided test.

Probability of an event in group 1 ...... .200

Probability of an event in group 2 ...... .400

Significance level ...................... .050

Number of equal

trials in each group Power

10.000 .166

20.000 .287

30.000 .402

40.000 .507

50.000 .599

60.000 .678

70.000 .744

80.000 .799

90.000 .843

100.000 .878

110.000 .906

120.000 .929

130.000 .946

140.000 .959

150.000 .969

HOW TO GET IT

The source code is available by anonymous ftp from

odin.mda.uth.tmc.edu. (129.106.3.17).

Source

/pub/unix/stplan-4.0-tar.Z

MSDOS Executable

/pub/stplan40.exe

This is an self-extracting file containing an MSDOS executable

version of Stplan plus documentation. The file was created with a

licensed copy of PkZip. STPLAN was compiled using the Watfor compiler

and so requires a 386 (or better) machine to run.

Barry W. Brown

Department of Biomathematics,

Box 237

University of Texas M. D.

Anderson Hospital

1515 Holcombe Blvd

Houston, TX 77030

bwb@odin.mda.uth.tmc.edu

internet address is (129.106.3.17)

The software described in the following announcement may be

useful for biomechanical studies. Most of us are familiar

(unfortunately) with the situation where statistical analysis

could not provide a good answer to the research question. This

software helps you to prevent such problems by considering

statistical analysis in the planning stage. The software is in

the public domain. I have not tried this, so comments are

welcome.

-- Ton van den Bogert, Biomch-L moderator

>From: bwb@odin.mda.uth.tmc.edu (Barry W. Brown)

>Newsgroups: comp.lang.fortran,sci.math.num-analysis,sci.math.stat,sci.stat.math,comp.programm ing,sci.stat.consult

>Subject: ANNOUNCE - Sample Size, Power, Etc. Program

>Date: 9 Nov 1993 15:49:34 GMT

>Organization: University of Texas M.D. Anderson Cancer Center

STPLAN 4.0

STPLAN performs power, sample size, and related calculations needed to

plan studies. Parameters of a test include those necessary to

describe the distributions under the null and alternative hypotheses,

sample sizes, significance levels, and power. Given values for all

but one parameter, STPLAN will calculate the value of that one

parameter.

The following testing situations are covered by STPLAN:

Studies with Outcomes Distributed According to the Binomial Distribution

One-sample test

Two-sample test

Two-sample above and below the median

Fisher's exact

Matched pairs test for equality of proportions

Conservative versus expensive treatment

Two-sample test in which one group is a historic control

K-sample

Case-control

Sample size correction for loss of subjects over time

Studies with Outcomes Distributed According to the Poisson Distribution

One-sample test

Two-sample test

Studies with Outcomes Distributed According to the Normal Distribution

One-sample test

Two-sample test, equal variances

Two-sample test, unequal variances

Two-sample log-normal

Studies with Outcomes Distributed According to the Exponential Distribution

One-sample test

Two-sample test

Studies whose Outcome is a Set of Survival Times.

Randomized clinical trial for exponential survival times

Comparison with a historic control - exponential survival

Randomized clinical trial - two different hazard rates depending on time

Studies whose Outcome is the Correlation Coefficient

One-sample test

MAJOR CHANGES IN 4.0

The major changes are: (1) the ability to produce tables of any one

quantity as a function of any other, and (2) a complete report format

that allows exact reconstruction of the calculation. In addition

three new testing calculations have been added.

A TASTE OF THE OUTPUT OF THE NEW VERSION

***** Two-sample Binomial (Arcsin approximation) *****

These calculations are for a two sided test.

Probability of an event in group 1 ...... .200

Probability of an event in group 2 ...... .400

Significance level ...................... .050

Number of equal

trials in each group Power

10.000 .166

20.000 .287

30.000 .402

40.000 .507

50.000 .599

60.000 .678

70.000 .744

80.000 .799

90.000 .843

100.000 .878

110.000 .906

120.000 .929

130.000 .946

140.000 .959

150.000 .969

HOW TO GET IT

The source code is available by anonymous ftp from

odin.mda.uth.tmc.edu. (129.106.3.17).

Source

/pub/unix/stplan-4.0-tar.Z

MSDOS Executable

/pub/stplan40.exe

This is an self-extracting file containing an MSDOS executable

version of Stplan plus documentation. The file was created with a

licensed copy of PkZip. STPLAN was compiled using the Watfor compiler

and so requires a 386 (or better) machine to run.

Barry W. Brown

Department of Biomathematics,

Box 237

University of Texas M. D.

Anderson Hospital

1515 Holcombe Blvd

Houston, TX 77030

bwb@odin.mda.uth.tmc.edu

internet address is (129.106.3.17)