Postdoctoral Research Assistant - Bio-Control Systems

Centre for Medical Engineering and Technology
Faculty of Science
University of Hull

This post is to support a joint EPSRC / BBSRC funded multi-disciplinary
project involving the Universities of Hull and York, concerned with the
application of Control Engineering methodologies to the biological
mechanisms responsible for the regulation and control of normal bone
turnover processes and the adaptation of bone in response to changes in
mechanical load.

The project requires research into the biological mechanisms that
control the remodelling of bone - the sensing role of osteocytes and the
communication provided by the lacuno-canalicular network - and
identification and application of engineering control methods that could
be used to simulate those biological control processes. This will
require the inclusion of representative cell population dynamics and
local and systemic signalling mechanisms. Issues of scaling will also be
examined, including consideration of the options for parallelisation and
implementation on a high performance computer for very large scale

The successful applicant will have a first degree in engineering or
possibly life sciences, together with a PhD, or equivalent experience,
in an engineering or biomechanics field. S/he must have experience of
relevant modern control engineering methodologies, with excellent C++
and/or Matlab programming skills. S/he will work closely with other
researchers working on bone modelling projects and the Control and
Intelligent Systems Engineering (C&ISE) Research group (at Hull
University) and bone biology experts (at York University).

This is a two year appointment.

For informal enquiries, please contact Dr M J Fagan, Centre for Medical
Engineering and Technology ( or Professor R Patton,
C&ISE, (, both at the University of Hull.

For an application pack, email: (quoting
ref. FS39).

Closing date: 8 June 2007

Dr M J Fagan
Director, Centre for Medical Engineering and Technology (CMET)
University of Hull
United Kingdom

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