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  • PhD in Biomechanics, University Paris 12/Paris Est

    Dear Biomch-L Subscribers,

    A PhD position is open in our group in the field of bone biomechanics.
    Please, forward this call to any person who might be interested.

    Best regards,

    Vittorio SANSALONE

    Laboratoire de Biomécanique et Biomatériaux Ostéo-Articulaires
    CNRS UMR 7052 (Laboratoire de Mécanique Physique)
    Faculté des Sciences et Technologie
    Université Paris 12 - Val de Marne
    61, Av. du Général de Gaulle, 94010 Créteil Cedex, France
    Téléphone : +33 1 45 17 15 72
    Fax : +33 1 45 17 14 33
    E-Mail : vittorio.sansalone@univ-paris12.fr

    ----------------------------------------
    * PhD studentship *
    Growth and remodelling of bone tissue: poromechanical behaviour,
    microstructure and biochemical coupling.

    * Location *
    Laboratory of Osteo-Articular Biomechanics and Biomaterials, UMR CNRS 7052
    Laboratory of Mechanics and Physics (http://www.univ-paris12.fr/lmp/)
    University Paris 12 - Val de Marne (Paris Est)
    61, Av. du Général de Gaulle, 94010 Créteil, France

    * Contacts *
    Salah Naili, naili@univ-paris12.fr, tel: +33 1 45 17 14 45
    Vittorio Sansalone, vittorio.sansalone@univ-paris12.fr, tel: +33 1 45 17 15 72

    * Deadline *
    Thursday, July 31, 2008

    * Eligibility *
    Students with a proper degree or expecting to obtain it by December 2008 are
    eligible.

    * Salary *
    20 000 EUR/year plus benefits; extra money available on condition.

    * Application procedure *
    Interested applicants should send their CV by e-mail. Applications will be
    accepted also after the deadline, until the position is filled.

    * Keywords *
    Biomechanics; Bone; Adaptation, Growth & remodelling; Poromechanics;
    Microstructure; Coupled multi-physics phenomena; Modelling & simulation.

    * Education and skills required *
    The candidate is expected to have a solid background in continuum mechanics
    (both solid and fluid mechanics). Previous knowledge of numerical methods
    (FEM, FDM, etc.) and scientific programming tools (C++, MatLab, etc.) is
    required. A keen interest for biomechanics and life sciences, as well as a
    penchant for multidisciplinary research are important assets.

    * Description *
    This PhD project focuses on the adaptation (growth and remodelling) of the
    bone tissue and its microstructure. Both mechanical and biochemical stimuli
    shall be considered to understand and predict mesoscopic bone properties,
    addressing in particular its poromechanical response. The general aim is to
    develop a biomechanical theory where bone is modelled as a porous medium whose
    microstructure adapts to the (mechanical and chemical) environment. The
    mesoscale properties of the evolving microstructure shall be obtained by means
    of suitable homogenization procedures. This will eventually lead to an
    effective macroscopic characterization of the poromechanical response of bone
    tissue. Of necessity, this research shall be multidisciplinary, since the
    coupling between mechanics, biology and chemistry will be its main theme.
    While doing most of his/her work in mechanics, the student will be asked to
    study also topics from biology and chemistry, under the guidance and in
    collaboration with experts in these disciplines. The biomechanical model shall
    be implemented in a computational code. Results from numerical simulations
    shall be eventually compared with experimental outcomes, in order to validate
    the model. This research work should provide us with a better understanding of
    adaptivity of bone tissue. Ultimately, it could lead to improvements on the
    existing therapeutic protocols and clinical practices.
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