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PhD vacancy on musculoskeletal modeling of orthopedic surgery -University of Twente - The Netherlands

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  • PhD vacancy on musculoskeletal modeling of orthopedic surgery -University of Twente - The Netherlands

    The Biomedical Engineering Department of the University of Twente in
    The Netherlands is currently looking for one more PhD student on an
    European Union funded project TLEMsafe: Improving safety and
    predictability of complex musculoskeletal surgery using a
    patient-specific navigation system. See below for the full description
    of the vacancy.

    The position should be filled soon, so we encourage interested
    applicants to reply a.s.a.p. and directly to this email.

    With kind regards,

    Dr. Marjolein van der Krogt
    Prof. Nico Verdonschot
    Prof. Bart Koopman


    Three PhD positions in Prediction of reconstructive surgery

    University of Twente. A place where talent emerges and develops.
    Students and staff are our valued core. Approximately 2700 scientists
    and professionals work together on groundbreaking research, relevant
    innovation and inspiring education for more than 8,500 students.

    The Faculty of Engineering Technology of the University of Twente has
    350 employees and 1700 students within its four clusters: Civil
    Engineering, Industrial Engineering, Mechanical Engineering and
    Sustainable Energy. In the Biomedical Engineering Department of the
    cluster of Industrial Engineering vacancies exist for:

    Three PhD positions on the prediction of the functional effects due to
    surgery on the musculoskeletal system of patients using the Twente
    Lower Extremity Model (TLEM).


    The University of Twente (UT) is involved in a European project aimed
    to improve patient safety and post-operative functionality of patients
    who have to undergo severe surgery to their musculoskeletal system.
    The starting point of the project is the Twente Lower Extremity Model
    (TLEM) which is a musculoskeletal model with which muscle forces can
    be calculated during all kinds of daily activities.

    In this project we want to develop patient-specific musculoskeletal
    models using automated 3-D image-analyzing tools to parameterize the
    musculoskeletal system of the patients.

    The patient-specific parameters are fed into a recently developed
    musculoskeletal model (TLEM) with which the patient-specific
    functional outcome can be predicted. The surgery that these patients
    need to undergo (due to for example a tumor or a revision of a hip) is
    subsequently simulated in the TLEM model (by removing for example a
    muscle in a tumor case) and the model predicts the functional effect
    of this. By measuring the functional outcome of the same patients
    (before and after surgery) we can check whether the model adequately
    predicts the effect of the surgery.The TLEM model is quite complex and
    not suitable for interaction with a surgeon. Therefore the model is
    made accessible using virtual reality algorithms. In this way a
    patient specific pre-planning tool is developed on with the surgeon
    can optimize his surgical plan. Once the optimal plan is selected,
    this is fed into a surgical-navigation system that allows the surgeon
    to reproduce the selected surgical plan during the actual surgery.

    The project is a true inter-disciplinary collaboration with experts
    from Denmark, Poland, Germany, Belgium and The Netherlands and covers
    scientific areas related to imaging, computer science, musculoskeletal
    modelling, patient care, surgery and functional outcome.

    The three PhD students will focus on the patient-specific
    musculoskeletal modeling using the TLEM model as a basis. TLEM will be
    further developed to incorporate the adaptive capacity of the patients
    after loss (or re-direction) of some parts of their musculoskeletal
    system. Furthermore, a link of the output of the TLEM model to the
    surgical navigation system is required. The clinical application
    requires that part of the activities are executed at the Radboud
    University Nijmegen Medical Centre in Nijmegen.

    The PhD students will collaborate closely with the other partners of
    the consortium that consists of European research institutes and
    business companies. Bachelor and master students will also be involved
    in the project and the candidates will have an important role in the
    daily supervision of these students. A modest contribution in the
    educational tasks will also be demanded.


    We are looking for highly motivated and enthusiastic researchers with
    a master degree in Mechanical or Biomedical Engineering or a closely
    related field, with outstanding results. A strong background in
    biomechanics and modeling is preferred. We seek for candidates with
    good team spirit, who like to work in an internationally oriented
    environment. Fluency in English is a requirement. An interview and a
    scientific presentation will be part of the selection procedure.


    We offer scientific education on a multidisciplinary subject. The
    assignment is for 4 years, with a go/no-go assessment at the end of
    the first year. The candidates are expected to finish the project with
    a PhD thesis and disseminate the results through patents (if
    applicable), publications in peer-reviewed journals and presentations
    at international conferences.

    Your starting salary will be € 2042,-,gross per month in the first
    year, leading up to € 2612, - gross per month in the last year,
    according to the Collective Labour Agreement for Dutch Universities.
    In addition, we offer our employees a broad package of secondary

    Information and application

    For more information, please contact prof. Bart Koopman (+31 53
    4894855, or prof. Nico Verdonschot (+31 6
    22400300, Applications for any of these
    PhD positions must include a Curriculum Vitae, a summary of your MSc
    thesis and a list of persons for reference purposes. Please send your
    application letter to with reference to
    vacancy number 10/006.