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  • Measuring spasticity

    Dear member,

    You may remember that I posted recently both here and on physio maulbase
    a request for info on measuring spasticity. This provoked a good and
    varied response leading me to believe that the whole business is in its
    infancy! As you will see there are a good number of references to follo
    up.

    In view of the response, I would like to chalenge the bioengineers
    (including me!) to produce some clear definitions of spasticity. It
    seems that the condition varies all the way from slight muscle stiffness
    (viscous damping?) all the way to a joint which can only be moved with
    extreme difficulty. Incidentally, there does not seem to be any work on
    measuirng this very severe spasticity. Why is that - is it toot
    difficult or do people thnk it is unimportant clinically?

    Let me know your thoughts

    Garth Johnson


    here are the replies:

    I am trying to build up some knowledge on biomechanical techniques for the
    measruement of spasticity. Could anyone interested let me know of techniques
    they use or are aware of. I am also sending this to the physio mailbase.

    Replies will be posted as usual

    Garth Johnson
    Centre for Rehabilitation and Engineering Studies (CREST)
    Stephenson Building
    University of Newcastle upon Tyne
    Newcastle upon Tyne NE1 7RU
    UK

    tel:+44-91-222-6196
    fax:+44-91-222-8600
    email: g.r.johnson@newcastle.ac.uk




    To: "G.R.Johnson"
    From: ikirtley@info.curtin.edu.au (Chris Kirtley)
    Subject: Re: Measurement of Spasticity
    Content-Type: text/plain; charset="us-ascii"
    Content-Length: 1493
    Status: O
    X-Status:

    Dear Garth,

    I looked into this a couple of months ago.

    I found a paper towards the end of my search which really put the rest into
    perspective:

    Joint Stiffness: Myth or Reality
    Mark Latash & Vladimir Zatsiorsky
    Human Movement Science 12 (1993): 653-692

    I urge you to read it FIRST!

    Also,

    Skeletal muscle tone & the misunderstood stretch reflex, Robert Davidoff
    Neurology 1992, 42: 951-963

    and

    Spasticity: quantitative measurements as a basis for assessing effectiveness
    of thereapeutic intervention
    Lehmann JF et al Arch Phys Med Rehab 70 (1989): 6-15

    In the end I became so disillusioned by what I read I gave up the idea of
    measuring it!

    Best wishes & best of luck!
    Chris

    __________________________________________________ _______________
    _/ Dr. Chris Kirtley
    MB ChB, PhD
    _/_/ _/ _/ _/_/_/ _/_/_/ _/ _/_/_/ ^
    Lecturer,
    _/ _/ _/ _/ _/ _/ _/ _/ _/ --_ / \
    Bio-engineering
    _/ _/ _/ _/ _/ _/ _/ _/ _/ /Perth \ Tel. +61
    9 381 0600
    _/ _/ _/ _/ _/ _/ _/ _/ _/ #_.---._/ Fax +61
    9 381 1496
    _/_/ _/_/_/ _/ _/ _/_/ _/ _/ _/ V
    ____________________________________________ School of
    Physiotherapy,
    U n i v e r s i t y of T e c h n o l o g y GPO Box U1987,
    Perth 6001, WA
    P e r t h, W e s t e r n A u s t r a l i a
    c.kirtley@info.curtin.edu.au
    __________________________________________________ _______________



    Date: Tue, 5 Jul 1994 16:28:10 +0800
    To: G.R.Johnson@newcastle.ac.uk
    From: ikirtley@info.curtin.edu.au (Chris Kirtley)
    Subject: Measuring Muscle Stiffness
    Content-Type: text/plain; charset="us-ascii"
    Content-Length: 2598
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    Garth...
    Here's a sample of what I got from BIOMCH-L. Note that I asked
    specifically
    about Impedance measurement rather than spasticity...

    >Dear Chris:
    >
    >There are a number of studies of endpoint or joint stiffness during one- or
    two-d motion. Names to look up include Robert Kearney, Ian Hunter, Kawato,
    David Bennett, Y.? Xu, Alesandro Mussa-Ivaldi and Reza Shadmehr.
    >These studies use different devices to apply perturbations; for example,
    Kearney and Hunter used a torque motor connected to a frame mounted at the
    subject's ankle, Mussa-Ivaldi and Shadmehr used a two DOF robotic arm
    >to perturb the subject's hand, and Xu and Bennett used an airjet device to
    perturb the subject's forearm during one-D elbow movements. The only person
    I know of who's attempted to make full 3-D impedance
    measurements is a friend of mine in the biomechanics lab at the Massachusetts
    Institute of Technology; his name's Denis Rancourt and his email address is
    boloria@gmc.ulaval.ca (he's working at the University of Laval
    while he finishes his PhD).
    >
    >One of the universal conclusions of the above studies is that one can make
    fairly repeatable impedance measurements, but the actual
    values one obtains are critically dependent on the technique used, so it is
    difficult to apply one person's measurements in a new situation.
    >
    >Oh, two other people you might also want to look at: John Dolan, from
    Carnegie Mellon, did 2-D impedance measurements at posture (for the arm) and
    Lacquiniti (I'm not sure I've got the spelling right)
    recently reported on impedances measured during a catching task.
    >
    >Hope this helps.
    >
    >Cheers,
    >
    >Tony Hodgson
    >ahodgson@hstbme.mit.edu
    >Laboratory for Biomechanics and Human Rehabilitation
    >3-143, MIT, 77 Mass Ave. Cambridge, MA USA 02139
    >

    __________________________________________________ _______________
    ____________
    _/ Dr. Chris Kirtley
    MB ChB, PhD
    _/_/ _/ _/ _/_/_/ _/_/_/ _/ _/_/_/ ^
    Lecturer,
    _/ _/ _/ _/ _/ _/ _/ _/ _/ --_ / \
    Bio-engineering
    _/ _/ _/ _/ _/ _/ _/ _/ _/ /Perth \ Tel. +61
    9 381 0600
    _/ _/ _/ _/ _/ _/ _/ _/ _/ #_.---._/ Fax +61
    9 381 1496
    _/_/ _/_/_/ _/ _/ _/_/ _/ _/ _/ V
    ____________________________________________ School of
    Physiotherapy,
    U n i v e r s i t y of T e c h n o l o g y GPO Box U1987,
    Perth 6001, WA
    P e r t h, W e s t e r n A u s t r a l i a
    c.kirtley@info.curtin.edu.au
    __________________________________________________ _______________
    ____________






    >From ngrj@eata Wed Jul 6 11:34:43 1994
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    From: P.van_Vliet@vme.ccc.nottingham.ac.uk
    Date: Tue, 5 Jul 94 10:03:15 BST
    Subject: spasticity
    To: g.r.johnson@newcastle.ac.uk
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    Hi Garth,
    Re-measuring spasticity, what about the idea of measuring the muscle stiffness
    element by using a device which delivers a
    series of controlled passive stretches to the spastic muscle, then measuring
    the resultant joint displacement? A ref. on this is
    Morris,ME et al. (1991) The effect of manual stretch on wrist flexor muscle
    spasticity following stroke. Proceedings of the 11th International Congress
    for the World Confederation of Physcial Therapy, pp496-498.
    from Paulette van Vliet

    >From ngrj@eata Wed Jul 6 11:35:10 1994
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    Message-Id:
    Date: Tue, 05 Jul 94 11:14:20 +0100 (WET)
    From: "Stephen J. Dorgan"
    Subject: Re: Measurement of Spasticity
    To: "G.R.Johnson"
    In-Reply-To: Your message of Tue, 5 Jul 1994 08:47:04 +0100
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    Garth,
    Sorry I can't help you out but I'd love to see some of the responses you
    get as I'm interested in spasticity myself.
    Many thanks in advance.
    Stephen.

    Stephen J. Dorgan
    Dept. of Electronic and Electrical Eng.
    National University of Ireland Tel.
    353-1-7061857
    University College Dublin
    Dublin 4, Ireland



    From: Jodi Nashman 594-1184
    Subject: Re: Measurement of Spasticity
    To: Multiple recipients of list BIOMCH-L
    Content-Type: text
    Content-Length: 375
    Status: O
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    I would suggest contacting Dr. Kristen Bowsher or Dr. Diane Damiano, both at
    the Motion Analysis Lab, Kluge Children's Rehabilitation Center at the
    University of Virginia. The telephone number is: 804:982-0848.
    Kristen's e-mail address is kab5z@virginia.edu. I am unsure of Diane's
    address. They have published in this area.

    Hope this is of some help.

    -- Jodi Nashman



    From: "A.W. Smith"
    To: G.R.Johnson@NEWCASTLE.AC.UK
    Subject: Re: Measurement of Spasticity
    Message-Id:
    Date: Tue, 5 Jul 1994 09:51:07 -0400
    Content-Type: text
    Content-Length: 2571
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    Currently, our therapists use one of two subjective scales: the Modified
    Ashworth and a simple 3-point scale (mild, moderate, severe). We have been
    involved in several drug-trial studies which use the pendulum
    test to calculate a relaxation index (so-called R2n - see Bajd and Vodovnic
    1984).
    These studies had the data collected by video so we are conducting our own
    validity and reliability tests on both the subjective scales and the more
    objective pendulum test. I have a PT Masters student who has just completed
    a small pilot study comparing the video R2n data from that of an
    electrogoniometer and this will be hopefully published as a technical note
    in the near future. Her thesis topic is developing a velocity-adjusted
    version of the Modified Ashworth Scale which we feel is the best compromise
    between the more technically-demanding aspects of the pendulum test with the
    clinical realities of too-little time and no access to even basic measuring
    equipment.

    Drew Smith PhD


    ************************************************** ***************
    *********
    * < =================================== >
    *
    * < The A.T. Jousse Research Laboratory >
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    * Andrew W. (Drew) Smith, PhD | Assistant Professor, U of
    Toronto *
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    awsmith@utcc.utoronto.ca *
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    Date: Tue, 05 Jul 94 12:15:55 EDT
    From: Sandra Olney
    Subject: Re: Measurement of Spasticity
    To: "G.R.Johnson"
    In-Reply-To: Your message of Tue, 5 Jul 1994 08:47:04 +0100
    Content-Type: text
    Content-Length: 716
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    As an aside, could you send info on Physio Mailbase you referred to?
    My colleague has just developed a neat instrument referred to as "twang" for
    want of a more sophisticed name. She (Brenda Brouwer) can be reached at
    Brouwerb@qucdn.queensu.ca. Dr. Carol Richards at Laval in Quebec
    used the KinCom for this purpose. I don't think she uses E-mail but her
    address is Ecole de Readaptation, Universite de Laval, Ste Foy, Quebec, Canada
    G1K 7P4.
    Might be best if she sent you an appropriate publication with description of
    use. Of course you have Katz article, Arch Phys med rehabil 70:144-155, 1989.
    Let me know what else you turn up. I would really like to hear.
    Torque motors are the Cadillac version, I guess.



    From: "Steve Mccaw"
    Sender: smccaw@rs6000.cmp.ilstu.edu
    Message-Id:
    To: G.R.Johnson@NEWCASTLE.AC.UK
    Subject: RE: Measurement of Spasticity
    Content-Type: text
    Content-Length: 993
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    You may want to see the text Muscles, masses & motion by Geoffrey Walsh,
    available from MacKeith Press (Oxford press). He deals
    extensively with the measurement of spasticity, among other forms of "muscle
    tone".
    Regards,
    Steve McCaw
    Dept of HPERD
    5120 Illinois State University
    Normal, Ill 61790-5120
    Phone (309)438-5307 Fax: (309)438-5559 e-mail SMCCAW@ILSTU.EDU



    To: g.r.johnson@newcastle.ac.uk
    From: zevric@casbah.acns.nwu.edu (Zev Rymer)
    Subject: Spasticity measurement
    Content-Type: text
    Content-Length: 629
    Status: O
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    Dear Garth:

    We have considerable experience in quantifying spasticity for research
    purposes, and I believe that the issues there are relatively
    straightforward. (I could send you some references and examples). THere are
    however no good approaches for routine clinical use. The answer to your
    question depends then on the proposed application of the measurement (ie
    research or clinical management), the limb (ie upper or lower), and the
    disease category (ie cerebral injury, spinal cord injury/MS/ALS,
    or CP).
    Sorry to get so complicated; its just that there are quite good solutions for
    limited objectives.

    Regards
    Zev Rymer


    >From ngrj@eata Wed Jul 6 11:37:03 1994
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    Subject: Re: Measurement of Spasticity
    From: "Dusan Simsik Csc. Doc. Ing."
    To: G.R.Johnson@NEWCASTLE.AC.UK
    Date: Wed, 6 Jul 1994 12:11:38 +0200
    In-Reply-To: from
    "G.R.Johnson" at Jul 5, 94 09:47:04 am
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    I reccomend to contact James Fee, Jr. from University of
    Delaware. His
    e-mail: fee@asel.udel.edu

    Dusan Simsik, Technical University, Letna 9, 04187 Kosice,
    Slovakia


    Dear Dr. Johnson,
    I would be very interested in the responses that you get from
    your posting. I would also like to ask you if you could provide me with the
    information to join the physiotherapy mailbase. I have tried on a couple of
    occasions without being successfull.
    Thank you
    Guy Simoneau Ph.D., P.T.
    Marquette University, Milwaukee, WI U.S.A.
    simoneaug@vmsf.csd.mu.edu



    From: Miss Mary Hannan
    Message-Id:
    Subject: Re: Measurement of Spasticity
    To: G.R.Johnson@NEWCASTLE.AC.UK
    Date: Wed, 6 Jul 94 17:49:19 BST
    Cc: mem1mh@surrey.ac.uk
    In-Reply-To: ; from
    "G.R.Johnson" at Jul 5, 94 8:47 am
    Mailer: Elm [revision: 70.85]
    Content-Type: text
    Content-Length: 2344
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    Garth,

    Hello. I hope that I can provide you with a little information on the
    measurement of spasticity.

    I am studying for a masters degree in biomedical engineering at the
    University of Surrey. I am doing my research project on the measurement of
    spasticity in the lower leg muscles of stroke patients who are
    using functional electrical stimulation to correct 'dropped-foot'. A long
    title but most scientific research has to be identified in
    detail I guess. I have been doing a literature study of ways of measuring
    spasticity. I don't have all the references right now, but I can give you a
    general summary.

    Clinical methods include the Pendulum Drop Test for testing the
    spasticity around the knee, tendon tap tests which measure
    the strength of the reflex with a force transducer I think, and spasticity
    scales such as the Ashworth scale which is a judgement made by an examiner as
    to the amount of resistance to movement. All of these have the disadvantage
    that the stimuli are not strictly controlled and rely on the examiner's
    judgement.

    Other measurement methods involve force transducers recording the
    strength of reflex contractions in muscles. Spasticity
    (hypertonicity) is accompanied by a 'heightened deep tendon reflex'which
    becomes over-sensitive to velocity of muscle stretch. Some
    experiments use passive movement, some use voluntary exertions, some use
    single cycle articulation, some use sinusoidal cycling for varying time
    periods. Commonly, there is a force transducer that is measuring
    the force of the involuntary (spastic) contractions that occur in the muscles.


    I am using passive movement of the ankle to elicit the stretch reflex
    response. I am getting there, but, there is still so much
    I have to learn about the intricacies of spasticity and its measurement. For
    my project, I actually have to design and build a clinical test rig. I am
    using a motor driven footplate and am trying to initially measure the torque
    by monitoring the current demanded by the motor since a force tansducer/load
    cell would be much too expensive for my
    meager project budget.

    I hope there is some useful info above. I can mail you some references
    if you like. Let me know.


    Mary Hannan
    Department of Mechanical Engineering
    Biomedical Engineering Group
    University of Surrey
    mem1mh@surrey.ac.uk




    From: Miss Mary Hannan
    Subject: More Spasticity Measurement..
    To: Multiple recipients of list BIOMCH-L
    Content-Type: text
    Content-Length: 1486
    Status: O
    X-Status:

    Hello Everyone,

    Garth Johnson's request for information about spasticity measurement
    prompted me to just broadcast this message about my
    project.

    I am studying for a masters degree in biomedical engineering at the
    University of Surrey. I am doing my research project on the measurement of
    spasticity in the lower leg muscles of stroke patients who are
    using functional electrical stimulation to correct 'dropped-foot'. A long
    title but most scientific research has to be identified in
    detail I guess.

    I am using passive movement of the ankle to elicit the stretch reflex
    response. I am getting there, but, there is still so much
    I have to learn about the intricacies of spasticity and its measurement. For
    my project, I actually have to design and build a clinical
    test rig. I am using a motor driven footplate which will be driven at
    constant angular speeds. I am trying to initially measure the
    torque by monitoring the current demanded by the motor since a force
    transducer/load cell would be much too expensive for my meager project budget.

    I'd just like to know if anyone had any experience in
    building a rig from scratch and taking measurements with load cell/force
    transducers or by monitoring the current into the motor. Any other comments
    ?????


    Thanks for your attention,


    Mary Hannan
    Department of Mechanical Engineering
    Biomedical Engineering Group
    University of Surrey
    mem1mh@surrey.ac.uk

    >From ngrj@eata Fri Jul 8 13:36:56 1994
    Received: from cheviot.ncl.ac.uk (cheviot.ncl.ac.uk
    [128.240.2.10]) by burnmoor.ncl.ac.uk (8.6.7/8.6.x-cf revision 8
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    (5.65cVUW/NCL-CMA.1.35 for G.R.JOHNSON@UK.AC.NEWCASTLE); Wed, 6
    Jul 1994 18:07:49 +0100
    From: DESOUZA@WLIHE.AC.UK
    Message-Id:
    Date: Wed, 6 Jul 94 18:06 BST
    To: G.R.JOHNSON@NEWCASTLE.AC.UK
    Subject: spasticity
    Content-Type: text
    Content-Length: 488
    Status: O
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    Hello Garth,
    re: your request to physio. mailbase for info.
    on the biomechanical measurement of spasticity.

    There is a section which addresses this in the paper:
    De Souza, L.H. and Musa, I.M. (1987) The measurement and assessment of
    spasticity. Clinical Rehab. vol. 1; pp. 89-96.

    Although now a little out of date, refs. are quoted, and I haven't noticed any
    new methods being generally applied in more
    recent times.

    Good luck, and greetings.

    Lorraine De Souza.

    DESOUZA@WLIHE.AC.UK



    From: David Robinson
    Subject: Orthoses and Tone
    To: physio@mailbase.ac.uk, davetel@cix.compulink.co.uk
    Reply-To: davetel@cix.compulink.co.uk
    Message-Id:
    X-List: physio@mailbase.ac.uk
    Sender: physio-request@mailbase.ac.uk
    Precedence: list
    Content-Type: text
    Content-Length: 314
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    I am doing a literature search on the effects of orthoses on the
    tone of children with cerebral palsy. If anybody knows of any relevant
    articles, I would appreciate any information anybody may have.

    Thanks
    Teleri Robinson
    Superintendent Physiotherapist
    Pinderfields Hospital, Wakefield. West Yorkshire. U.K.




    From: Bjorg Fallang
    Sender:
    Organization: Bislet h gskolesenter
    To: g.r.johnson@newcastle.ac.uk
    Subject: Ang.: Measurement of Spasticity (fwd)
    X-Mailer: XGATE 3.01.b15F MHS to SMTP Gateway
    Content-Type: text
    Content-Length: 376
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    Hello
    I am sorry I do not think I can give you any articles. Perhaps
    Tony Szturm at the University of Manitoba has good articles or
    contacts to give you? His email is: ptsturm@ccu.umanitoba.ca
    I would be glad to receive a copy of the summary of information
    you get.

    Bjorg Fallang
    Bislet College Dept. of Physiotherapy
    Pilestredet 56, 0167 Oslo, Norway
    FAX: 47 22 45 42 05
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