Dear netters,
The following are my original request for information on image analysis
systems and a summary of the replies. I appreciated all your help.
Original request
================================================== ===============
>
>I am looking for informations on systems capable of scanning the x-ray
>pictures and histological slides of bone and soft tissue, and possessing
>some image processing and analysis power. I have some experience with
>a system called MagiScan produced by Joyce Loebl, England. I would be
>very grateful for information of any other systems such as manufacturer,
>functions, prices.
>
>Lang Yang, PhD
>Bioengineering Unit
>University of Strathclyde
>Glasgow
>Scotland
>
>
================================================== ===================
Replies
================================================== ===================
Date: Wed, 26 Apr 1995 22:33:51 -0400
From: drl10@psu.edu (David Lemmon)
We use a simple setup of a light table with a video camera mounted above it.
The video camera is attached to a video image capturing board on a Macintosh
computer. We use a program called "ColorSnap" to capture the image on
screen and save it as a TIFF file. Then the image can be analzyed using
"NIH Image", a free program available through the internet. You need to
calibrate the intensities of the image to do any meaningful analyses, of
course -- I'm not sure how you would want to do that. If you are interested
in more detailed information on our setup, let me know.
David R. Lemmon, Ph.D.
Center for Locomotion Studies (CELOS)
10 IM Building
The Pennsylvania State University
University Park, PA, 16802 USA
Phone: 814-865-1972
FAX: 814-863-4755
------------------------------------------------------------
Date: Wed, 26 Apr 1995 12:18:27 -0500 (EST)
From: Spadaroj@VAX.CS.HSCSYR.EDU (Joe Spadaro)
I would be interested in the results of your search as this is a constant
need in our work too.
I would like to offer a poor man's method:
I have photographed x-rays or slides to 35mm slide or negative
film, scanned them into tiff or pict files using a Nikon Coolscan scanner
(about $1800) and then manipulated and measured denities and geometries
using NIH IMAGE program (free). This is not instantaneous, of corse, and
requires a camera with a macro lens and a computer (I use a Macintosh 610).
Joe Spadaro
Joe Spadaro, Ph.D.
S.U.N.Y. Health Science Center - Syracuse
spadaroj@vax.cs.hscsyr.edu
--------------------------------------------------------------------
From: R A Hillam
Date: Thu, 27 Apr 1995 11:10:14 +0100 (BST)
In reply to your query on image analysis, we have just bought a new system
which is excellent. It is a system called Osteomeasure, an American system.
I suggest you contact Glenn Wakley, our histomorphometrist who chose and
purchased the sytem. He has had extensive experience of Osteomeasure in
the Mayo Clinic but he looked at other systems eg Bioquant before buying
this for our department. He is away for a short time in the US. His
E-mail address is:
Glenn.Wakley@bris.ac.uk and you can contact him here by phone on:
0117-9287401 or 0117-9287418
regards
Richard Hillam
---------------------------------------------------
Date: Thu, 27 Apr 1995 11:42:44 +0100 (BST)
From: Alison Cutts
I've improvised with available equipment to get X-ray images into CAD
packages for dimensioning etc preliminary to prosthesis desgin. I used a
flatbed scanner (HPScanjet), placing the X-ray on the glass and
backlighting it with a desklamp placed carefully above. Scan image
quality was reasonably good. I also traced the outlines of the specific
bones I required and scanned these in too, and admittedly these latter
bitmaps were more versatile for subsequent analysis.
Bitmap processing was via Coreltrace and Coreldraw to produce a Windows
metafile which can be imported into AutoCAD or AutoSKETCH. These images
are undistorted and can be analysed using the full power of the CAD packages.
Although this was a rather quick and dirty method, it gave the
information I needed. I might possibly extend my investigations and
should any money become available, I would be interested in specialist
equipment. I'd be interested to know a bit more about the MagiScan system
you mentioned; perhaps you could forward any information about other
systems you get?
Best wishes
Alison Cutts PhD
Lecturer in Biomechanics, MMM Eng, Univ. Newcastle upon Tyne.
-------------------------------------------------------------
Date: Thu, 27 Apr 1995 09:08:11 -0400 (EDT)
From: John Lawrence
Try Charles F. Fischer at the University of Kentucky. He is an
independent consultant writing software for digitizing and enhancing MRI
images for the Department of Cardiology at the UK Medical Center. His
e-mail address is:
fischer@bme1.image.uky.edu.
Good luck!
John H. Lawrence III, Ph.D.
Center for BIomedical Engineering
University of Kentucky
Lexington, KY 40506-0070
(606) 257-3783
------------------------------------------------------------
Date: Thu, 27 Apr 95 14:44:58 EDT
From: rad zdero
i myself am in a similar process....products like Moka & Java from
Jandel Corp (California/ USA) may be useful for dimensional analysis of images
.....prices are up to $ 2000 U.S., as far as i can recall...i think Java is no
longer available but Moka is its successor...if you're looking for 3D
reconstruction software, PC3D from Jandel may be useful....
-------------------------------------------------------------
Date: Fri, 28 Apr 1995 11:46:37 +0000
From: anders@ull.biomeklab.aau.dk (Anders Odgaard)
For stereological measures you might be interested in a product called the
C.A.S.T.-GRID SYSTEM being distributed by OLYMPUS DK. I'm not familiar with
the product, but I have seen several adds describing it. It's supposed to
give access to the new stereological methods, which I don't think you'll find
in most other systems. Most systems simply grab an image and allows some
manipulation without many quantitative fascilities.
The contact address would be
Olympus Denmark A/S
23A Produktionsvej
DK-2600 Glostrup
phone: +45 4284 5858
fax: +45 4284 2055
and I'm sure they'll be happy to provide further information.
Best regards,
Anders Odgaard, M.D.
-------------------------------------------------------------
Date: 28 Apr 95 09:59:42 EDT
From: Jonathan Black
I suggest that you contact:
Dr. L. Dooley
Dept. of Bioengineering
Clemson University
Clemson, SC 29634
Internet:dooley@@eng.clemson.edu
He may be able to help you.
Sincerely,
Jonathan Black, PhD, FBSE
IMN Biomaterials
409 Dorothy Drive
King of Prussia, PA 19406
--------------------------------------------------------
From: Tim.Skerry@bristol.ac.uk (TM. Skerry)
Date: Sat, 29 Apr 1995 11:43:08 +0100 (BST)
Calll
Charlie Bleau
Osteometrics Inc,
2103 N Decatur Rd,
Suite 140,
Atlanta,
GA 30033-5307
tel 404 634 4222
fax 404 982 9478
He is the VP of Osteometrics,
which makes Osteomeasure - a bone specific software package, which he can
supply with more general image analysis software and all the necessary
hardware.
He is very helpful, and friendly, and the systems are very user friendly,
(better and easier than magiscan) and not too expensive.
We paid around 16K for hardware and software to attach to our existing
microscope and it does everything we need and much more.
If you do call, mention my name, as I'd like charlie top know I feel
positive about his stuff.
I really can't reccomend him and the equipment too highly.
__________________________________________________ __________________________
Date: Mon, 08 May 1995 07:04:40 +0000 (GMT)
From: kokelly@ccvax.ucd.ie (Kevin O'Kelly)
I've had great success with NIH Image which I use for analysing SEM's of
cancellous bone. It's one of the more powerful image analysis packages
I've come across and very easy to configure using macros. If you want to
the source code is available and you can write user routines. There is a
tremendous amount of support available via a specific bulletin board for
users. You can get very quick and accurate responses to queries. You will
more then likely find someone has done something along your lines as well.
The program, documentation and source code are all public domain and
available via anaonymous ftp from zippy.nimh.nih.gov. N.B. Only a Mac
version exists.
Kevin O'Kelly e-mail: kokelly@ccvax.ucd.ie
Bioengineering Research Centre, tel: +353 (1) 706-1987
Mechanical Engineering Department, fax: +353 (1) 283-0534
University College Dublin,
Belfield, Dublin 4,
Ireland.
================================================== ======================
The following are my original request for information on image analysis
systems and a summary of the replies. I appreciated all your help.
Original request
================================================== ===============
>
>I am looking for informations on systems capable of scanning the x-ray
>pictures and histological slides of bone and soft tissue, and possessing
>some image processing and analysis power. I have some experience with
>a system called MagiScan produced by Joyce Loebl, England. I would be
>very grateful for information of any other systems such as manufacturer,
>functions, prices.
>
>Lang Yang, PhD
>Bioengineering Unit
>University of Strathclyde
>Glasgow
>Scotland
>
>
================================================== ===================
Replies
================================================== ===================
Date: Wed, 26 Apr 1995 22:33:51 -0400
From: drl10@psu.edu (David Lemmon)
We use a simple setup of a light table with a video camera mounted above it.
The video camera is attached to a video image capturing board on a Macintosh
computer. We use a program called "ColorSnap" to capture the image on
screen and save it as a TIFF file. Then the image can be analzyed using
"NIH Image", a free program available through the internet. You need to
calibrate the intensities of the image to do any meaningful analyses, of
course -- I'm not sure how you would want to do that. If you are interested
in more detailed information on our setup, let me know.
David R. Lemmon, Ph.D.
Center for Locomotion Studies (CELOS)
10 IM Building
The Pennsylvania State University
University Park, PA, 16802 USA
Phone: 814-865-1972
FAX: 814-863-4755
------------------------------------------------------------
Date: Wed, 26 Apr 1995 12:18:27 -0500 (EST)
From: Spadaroj@VAX.CS.HSCSYR.EDU (Joe Spadaro)
I would be interested in the results of your search as this is a constant
need in our work too.
I would like to offer a poor man's method:
I have photographed x-rays or slides to 35mm slide or negative
film, scanned them into tiff or pict files using a Nikon Coolscan scanner
(about $1800) and then manipulated and measured denities and geometries
using NIH IMAGE program (free). This is not instantaneous, of corse, and
requires a camera with a macro lens and a computer (I use a Macintosh 610).
Joe Spadaro
Joe Spadaro, Ph.D.
S.U.N.Y. Health Science Center - Syracuse
spadaroj@vax.cs.hscsyr.edu
--------------------------------------------------------------------
From: R A Hillam
Date: Thu, 27 Apr 1995 11:10:14 +0100 (BST)
In reply to your query on image analysis, we have just bought a new system
which is excellent. It is a system called Osteomeasure, an American system.
I suggest you contact Glenn Wakley, our histomorphometrist who chose and
purchased the sytem. He has had extensive experience of Osteomeasure in
the Mayo Clinic but he looked at other systems eg Bioquant before buying
this for our department. He is away for a short time in the US. His
E-mail address is:
Glenn.Wakley@bris.ac.uk and you can contact him here by phone on:
0117-9287401 or 0117-9287418
regards
Richard Hillam
---------------------------------------------------
Date: Thu, 27 Apr 1995 11:42:44 +0100 (BST)
From: Alison Cutts
I've improvised with available equipment to get X-ray images into CAD
packages for dimensioning etc preliminary to prosthesis desgin. I used a
flatbed scanner (HPScanjet), placing the X-ray on the glass and
backlighting it with a desklamp placed carefully above. Scan image
quality was reasonably good. I also traced the outlines of the specific
bones I required and scanned these in too, and admittedly these latter
bitmaps were more versatile for subsequent analysis.
Bitmap processing was via Coreltrace and Coreldraw to produce a Windows
metafile which can be imported into AutoCAD or AutoSKETCH. These images
are undistorted and can be analysed using the full power of the CAD packages.
Although this was a rather quick and dirty method, it gave the
information I needed. I might possibly extend my investigations and
should any money become available, I would be interested in specialist
equipment. I'd be interested to know a bit more about the MagiScan system
you mentioned; perhaps you could forward any information about other
systems you get?
Best wishes
Alison Cutts PhD
Lecturer in Biomechanics, MMM Eng, Univ. Newcastle upon Tyne.
-------------------------------------------------------------
Date: Thu, 27 Apr 1995 09:08:11 -0400 (EDT)
From: John Lawrence
Try Charles F. Fischer at the University of Kentucky. He is an
independent consultant writing software for digitizing and enhancing MRI
images for the Department of Cardiology at the UK Medical Center. His
e-mail address is:
fischer@bme1.image.uky.edu.
Good luck!
John H. Lawrence III, Ph.D.
Center for BIomedical Engineering
University of Kentucky
Lexington, KY 40506-0070
(606) 257-3783
------------------------------------------------------------
Date: Thu, 27 Apr 95 14:44:58 EDT
From: rad zdero
i myself am in a similar process....products like Moka & Java from
Jandel Corp (California/ USA) may be useful for dimensional analysis of images
.....prices are up to $ 2000 U.S., as far as i can recall...i think Java is no
longer available but Moka is its successor...if you're looking for 3D
reconstruction software, PC3D from Jandel may be useful....
-------------------------------------------------------------
Date: Fri, 28 Apr 1995 11:46:37 +0000
From: anders@ull.biomeklab.aau.dk (Anders Odgaard)
For stereological measures you might be interested in a product called the
C.A.S.T.-GRID SYSTEM being distributed by OLYMPUS DK. I'm not familiar with
the product, but I have seen several adds describing it. It's supposed to
give access to the new stereological methods, which I don't think you'll find
in most other systems. Most systems simply grab an image and allows some
manipulation without many quantitative fascilities.
The contact address would be
Olympus Denmark A/S
23A Produktionsvej
DK-2600 Glostrup
phone: +45 4284 5858
fax: +45 4284 2055
and I'm sure they'll be happy to provide further information.
Best regards,
Anders Odgaard, M.D.
-------------------------------------------------------------
Date: 28 Apr 95 09:59:42 EDT
From: Jonathan Black
I suggest that you contact:
Dr. L. Dooley
Dept. of Bioengineering
Clemson University
Clemson, SC 29634
Internet:dooley@@eng.clemson.edu
He may be able to help you.
Sincerely,
Jonathan Black, PhD, FBSE
IMN Biomaterials
409 Dorothy Drive
King of Prussia, PA 19406
--------------------------------------------------------
From: Tim.Skerry@bristol.ac.uk (TM. Skerry)
Date: Sat, 29 Apr 1995 11:43:08 +0100 (BST)
Calll
Charlie Bleau
Osteometrics Inc,
2103 N Decatur Rd,
Suite 140,
Atlanta,
GA 30033-5307
tel 404 634 4222
fax 404 982 9478
He is the VP of Osteometrics,
which makes Osteomeasure - a bone specific software package, which he can
supply with more general image analysis software and all the necessary
hardware.
He is very helpful, and friendly, and the systems are very user friendly,
(better and easier than magiscan) and not too expensive.
We paid around 16K for hardware and software to attach to our existing
microscope and it does everything we need and much more.
If you do call, mention my name, as I'd like charlie top know I feel
positive about his stuff.
I really can't reccomend him and the equipment too highly.
__________________________________________________ __________________________
Date: Mon, 08 May 1995 07:04:40 +0000 (GMT)
From: kokelly@ccvax.ucd.ie (Kevin O'Kelly)
I've had great success with NIH Image which I use for analysing SEM's of
cancellous bone. It's one of the more powerful image analysis packages
I've come across and very easy to configure using macros. If you want to
the source code is available and you can write user routines. There is a
tremendous amount of support available via a specific bulletin board for
users. You can get very quick and accurate responses to queries. You will
more then likely find someone has done something along your lines as well.
The program, documentation and source code are all public domain and
available via anaonymous ftp from zippy.nimh.nih.gov. N.B. Only a Mac
version exists.
Kevin O'Kelly e-mail: kokelly@ccvax.ucd.ie
Bioengineering Research Centre, tel: +353 (1) 706-1987
Mechanical Engineering Department, fax: +353 (1) 283-0534
University College Dublin,
Belfield, Dublin 4,
Ireland.
================================================== ======================