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  • APA Funding Bulletin

    Dear Biomch-L readers,

    Those of you interested in obtaining (US-based) research funding information
    may find a wealth of possibilities through APASD-L@VTVM2.BITNET, the American
    Psychological Association's Research Psychology Funding Bulletin. Just send
    the one-line request INDEX APASD-L to LISTSERV@VTVM2.BITNET in order to obtain
    (by NETDATA or email) a list of all files currently available. By way of
    example, I am reposting below the file NIDR ORALMOTO, in view of its relation-
    ship to the scope of Biomch-L. Another, interesting file is AHCPR MEDICAL on
    dissemination of research results into clinical practice.

    With kind regards,

    Herman J. Woltring, Eindhoven/NL

    +++++NIDR ORALMOTO++++++++++++++++++++++++++++++++++++++++++ +++++++++++++++++

    BASIC AND CLINICAL RESEARCH ON NORMAL AND IMPAIRED ORAL-MOTOR FUNCTION

    National Institute of Dental Research
    National Institute on Deafness and Other Communicative Disorders

    Application Receipt Dates: June 1, October 1, February 1

    The Craniofacial Anomalies, Pain Control and Behavioral Research Branch
    of the National Institute of Dental Research (NIDR) invites research
    grant applications to study neurobiological and physiological processes
    controlling coordinated oral movements (such as mastication) and to
    expand knowledge concerning relationships between oral-motor function
    and dental procedures or abnormal oral conditions. In addition, the
    Division of Communication and Neurosensory Diseases of the National
    Institute on Deafness and Other Communicative Disorders (NIDCD) invites
    research grant applications to study processes involved in normal and
    disordered speech production and/or swallowing.

    The NIDR and NIDCD seek to accelerate research progress in this area by
    inviting meritorious applications dealing either with fundamental
    processes underlying the control of coordinated oral movements, or with
    clinically relevant aspects of oral-motor function.

    BACKGROUND

    Considerable scientific progress has been made over the past decade
    toward delineating neurobiological processes controlling limb movements
    and locomotion, respiratory movements, and eye movements. In contrast,
    relatively little attention has been directed toward understanding
    neurobiological and physiological processes involved in coordinated oral
    movement, except as they directly affect speech production. Yet oral
    motor behaviors-- including those involved in mastication, drinking, and
    suckling-- have important biological significance and remain among the
    most fundamental behaviors required for survival. Movements of the jaw
    and the surrounding musculature are integrally involved, in animals and
    in humans, in tasks as diverse as manipulating objects, attack and
    defense, communicating through facial expressions, and producing
    vocalizations.

    RESEARCH GOALS

    Fundamental studies are needed to delineate fully the neural pathways
    and processes underlying oral-motor behaviors. Recent research
    indicates that four major brain stem motor pools (trigeminal, facial,
    vagal, and hypoglossal) are involved in oral-motor behaviors. Two
    distinct neural networks governing rhythmic jaw movements (chewing) and
    some of the movements involved in drinking (lapping-like movements) have
    also recently been demonstrated in animals. However, knowledge of the
    structures and processes involved in initiation, control and
    coordination of oral movements remains very incomplete. Suitable topics
    for fundamental research include, but are not limited to: studies of
    the anatomical and physiological significance of connections between
    nuclei in the neural networks involved in oral-motor control; studies of
    the neuroanatomical and physiological characteristics of outputs from
    these neural networks to motoneurons; studies of the processes and
    structures involved in input from other parts of the central nervous
    system to the neural networks controlling oral-motor behaviors; and
    studies of the neurochemical process (i.e., neurotransmitters and
    neuromodulators) involved in activation and operation of these neural
    networks.

    Though some sound methodologies have been developed to assess oral-motor
    function both in the laboratory and natural environments, procedures for
    evaluating oral-motor function require additional development and
    standardization. Assessments may include, though are not limited to,
    measurement of factors such as chewing efficiency, muscular fatigue,
    biting force, limitations of mandibular movements. Also needed are
    studies clarifying how adaptation to morphologic change occurs within
    the oral-motor system when, for example, teeth are removed, dentures are
    inserted, or orthodontic treatment produces tooth movement. Of
    additional interest are improved approaches for tracking and monitoring
    complex movement patterns, evaluating associations between growth and
    development and oral-motor function, and for developing adequate
    mathematical models of repetitive oral-motor behaviors and complex
    movement patterns.

    Other clinical research topics may include, though are not limited to:
    relationships between oral-motor function and oral pathologies (e.g.,
    TMJ pain, severe tooth wear or mobility) or relationships between
    oral-motor function and dental treatment failures (e.g., broken or
    abraded restorations, orthodontic relapses, failure to adapt to dental
    prostheses). In addition studies of pathological conditions involving
    disturbances of oral-motor function (e.g., tardive dyskinesia, coma,
    stroke or bruxism) are encouraged, particularly as they relate to
    expanding understanding of mechanisms underlying motor control.

    Applicants are encouraged to contact NIDR staff prior to applying.
    Contact:

    Patricia S. Bryant, Ph.D.
    Health Scientist Administrator
    Craniofacial Anomalies, Pain Control
    and Behavioral Research Branch
    National Institute of Dental Research
    Westwood Building, Room 506
    Bethesda, Maryland 20892-4500
    Telephone: (301) 496-7807

    Applicants interested in oral motor function as related to speech
    production or swallowing should, prior to applying, contact Dr. Judith
    A. Cooper at the address/telephone number indicated below.

    Judith A. Cooper, Ph.D.
    Health Scientist Administrator
    Division of Communication and Neurosensory Disorders
    National Institute of Deafness and Other Communicative Diseases
    Federal Building, Room 1C06
    7550 Wisconsin Avenue
    Bethesda, Maryland 20892
    Telephone: (301) 496-5061
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