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  • Muscle Fatigue

    I have been asked to post the following memo on biomch-l as a service to
    interested subscribers. Please note that I receive no financial gain relate=
    to this announcement. =20

    DATE: December 21, 1995

    M E M O R A N D U M

    TO: Attendees, International Conference on Neural and
    Neuromuscular Aspects of Muscle Fatigue, Miami, FL,
    Nov. 10-13, 1994.

    =46ROM: Doug Stuart, Conference Chair and for the other
    organizers (Simon Gandevia, Roger Enoka, Alan
    McComas and Christine Thomas-Local Coordinator).

    RE: Availability of a new research monograph on muscle
    fatigue at a reduced (bulk-order) price.

    Greetings from Tucson! Many of the speakers and discussants
    and chairs at our 1994 fatigue conference have participated
    in the publication of a new research monograph, Fatigue:
    Neural and Muscular Mechanisms, with the conference
    organizers as editors. This monograph was published by the
    Plenum Publishing Corporation in November, 1995. Its retail
    price is $US125. There are no royalties for the editors
    and other authors. A copy of the table of contents is

    As promised in our 1994 Miami Conference Proceedings, this
    volume is being made available to conference attendees at a
    reduced price ($US57; including postage cost) provided you
    do the following two things by January 31, 1996. Please note
    that you may order as many copies as you like.

    1. Make out your payment check or money order in US dollars to "The=
    of Arizona - Acct No 235040", and mail to Dr. Douglas Stuart, Department of
    Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724, US=
    Please insure that it will arrive in Tucson no later than January 31, 1996.

    2. Immediately E-mail (DGStuart@Mail.Arizona.Edu) or fax
    (520-626-2383) Dr. Stuart:
    2.1 Confirm or revise your regular mail address, as it appeared in the=
    Proceedings of the 1994 Miami conference.
    2.2 Affirm that you have sent me your payment under separate cover.

    On February 15, 1996, I will send Plenum the bulk-order payment and updated =
    address labels, and your book(s) will be mailed to you by Plenum shortly=20

    If you were the author or co-author of a chapter in the volume, please note =
    in a separate mailing, primary authors will shortly receive a complimentary =
    from Plenum, as will senior co-authors who attended the Miami conference. =
    However, we assume that all this group will appreciate the opportunity to=20
    purchase additional copies at the reduced bulk-order price.

    The editors believe that the 505-page book, which addresses issues from the=
    forebrain to the contractile proteins, is of the highest quality and, as=
    is a fitting tribute to Brenda Bigland-Ritchie. It has 2 prologue and 37=20
    subsequent chapters. In all ways, we believe you will be proud to own
    the book and will find it of particular value as both a source of reference=
    an inspiration for lectures, trainee review sessions, and research on muscle=
    fatigue. Furthermore, your departmental/institutional library is sure
    to appreciate your inclusion of a copy for their unit. Similarly, you=
    have colleagues who would like to be included in your personal component of=
    bulk order. They may be included under their own names, or under your name.

    Although there will be no post-symposium volume as was originally intended,=
    summary of the conference, with commentaries and abstracts, will appear as a=
    supplement to Muscle & Nerve in either January or February of 1996.

    Thank you for your consideration of this information. If further details=
    required, please contact me.

    Enclosure: Contents of Fatigue: Neural and Muscular
    =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3 D=3D=3D=3D=3D=3D=3D=3D=3D=
    =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3 D=3D=3D=3D=3D=3D=3D=3D=3D=
    Looking Back Brenda Bigland-Ritchie (New Haven)

    The Scientific Contributions of Brenda Bigland-Ritchie C.K.
    Thomas, R.M. Enoka, S.C. Gandevia, A.J. McComas and D.G.

    Section I: Fatigue of Single Muscle Fibers
    1. Myofibrillar Fatigue versus Failure of Activation
    K.A.P. Edman
    2. Mechanisms of Excitation-Contraction Coupling Relevant
    to Skeletal Muscle Fatigue D. G. Stephenson, G.D. Lamb,
    G.M.M. Stephenson and M.W. Fryer
    3. The Role of Intracellular Acidosis in Muscle Fatigue
    D.G. Allen, H. Westerblad and J. L=E4nnegren
    4. Role of Interstitial Potassium G. Sj=F8gaard and A.J.

    Section II: Fatigue at the Neuromuscular Junction
    5. Fatigue at the Neuromuscular Junction: Branch Point vs.
    Presynaptic vs. Postsynaptic Mechanisms G.C. Sieck and
    6. The Role of the Sarcolemma Action Potential in Fatigue
    A.J. Fuglevand
    7. Single Fiber Electromyography in Studies of
    Neuromuscular Function J.V. Trontelj and E. St=E5lberg

    Section III: Fatigue of Single Motor Units
    8. Intrinsic Properties of Motoneurons: Implications for
    Muscle Fatigue A. Sawczuk, R.K. Powers and M.D. Binder
    9. Neuromuscular Frequency Coding and Fatigue D. Kernell
    10. Human Motor Units Studied by Spike-Triggered Averaging
    and Intraneural Motor Axon Stimulation C.K. Thomas
    11. Human Units Studied by Intramuscular Microstimulation
    J.M. Elek and R. Dengler

    Section IV: Metabolic Fatigue Studied with NMR Techniques
    12. Bioenergetics and Muscle Cell Types M.J. Kushmerick
    13. Metabolic Correlates of Fatigue from Different Types of
    Exercise in Man N.K. V=F8llestad
    14. Mechanisms of Human Muscle Fatigue: Quantitating the
    Contribution of Metabolic Factors and Activation
    Impairment R.G. Miller, J.A. Kent-Braun, K.R. Sharma
    and M.W. Weiner
    15. Emerging Opportunities with NMR L.A. Bertocci

    Section V: CNS Issues: The Case for Segmental Motor
    16. Variable-Frequency Stimulation Patterns for the
    Optimization of Force during Muscle Fatigue: Muscle
    Wisdom and the Catch-like Property S.A. Binder-Macleod
    17. Overview: Potential Role of Segmental Motor Circuitry in
    Muscle Fatigue U. Windhorst and G. Boorman
    18. The Fusimotor System: Its Role in Fatigue K-E. Hagbarth
    and V.G. Macefield
    19. Role of Muscle Afferents in the Inhibition of
    Motoneurons During Fatigue S.J. Garland and M.P Kaufman

    Section VI: CNS Issues: The Case for Central Fatigue
    20. Central Fatigue: Critical Issues, Quantification and
    Practical Implications S.C. Gandevia, G.M. Allen and
    21. Single-Trial Readiness Potentials and Fatigue D.
    Popivanov, A. Mineva and J Dushanova
    22. The Senses of Effort and Force During Fatiguing
    Contractions L.A. Jones
    23. Tryptophan, 5-Hydroxytryptamine and a Possible
    Explanation for Central Fatigue E.A. Newsholme and E.

    Section VII: Task Dependency of Fatigue Mechanisms
    24. The Significance of Motor Unit Variability in Sustaining
    Mechanical Output of Muscle A.J. Sargeant and D.A
    25. Intramuscular Pressures for Monitoring Different Tasks
    and Muscle Conditions O.M. Sejersted and A.R. Hargens
    26. Task-Dependent Nature of Fatigue in Single Motor Units
    B.R. Botterman
    27. Task-Dependent Factors in Fatigue of Human Voluntary
    Contractions. B. Bigland-Ritchie, C.L. Rice, S. J.
    Garland and M.L. Walsh.

    Section VIII: Integrative Systems Issues
    28. Fatigue and the Design of the Respiratory System S.L.
    Lindstedt and H. Hoppeler
    29. An Integrative View of Lmitations to Muscular
    Performance J.A. Dempsey and M.A. Babcock
    30. Respiratory Muscle Fatigue D.K. McKenzie and F.
    31. Fatigue of Jaw Muscles and Speech Mechanisms T.S. Miles
    and M.A. Nordstrom

    Section IX: Fatigue of Adapted Systems: Overuse, Underuse and
    32. Fatigue in Adapted Systems: Overuse and Underuse
    Paradigms T. Gordon
    33. Associations Between Muscle Soreness, Damage, and
    Fatigue P.M. Clarkson and D.J. Newham
    34. Muscle Fatigue in Old Animals: Unique Aspects of Fatigue
    in Elderly Humans J.A. Faulkner and S.V. Brooks
    35. Historical Perspective: A Framework for Interpreting
    Pathobiological Ideas on Human Muscle Fatigue R.H.T.
    Edwards, V. Toescu and H. Gibson
    36. Fatigue Brought on by Malfunction of the Central and
    Peripheral Nervous Fystems A.J. McComas, R.G. Miller
    and S.C. Gandevia

    37. Neurobiology of Muscle Fatigue: Advances and Issues
    S.C. Gandevia, R.M. Enoka, A.J. McComas, D.G. Stuart
    and C.K.Thomas.

    Roger M. Enoka, Ph.D.
    Department of Biomedical Engineering/Wb3
    Cleveland Clinic Foundation
    9500 Euclid Avenue
    Cleveland, OH 44195, USA

    Phone: 216-444-1805
    =46ax: 216-444-9198