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1. Resume about tantalum implants and the usage of them

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  • 1. Resume about tantalum implants and the usage of them


    1. Resume about Tantalum implants and the usage of them.

    Thank you very much to everybody's help.
    This first resume isn't complete and has only a few information about
    Tantalum and its usage. I will add more, until I got them.

    I found some good information on the page of the University of
    Sheffield, England (

    The main information about Tantalum (Ta) are:
    Used to make alloys with desirable properties such as high melting
    point (3293 K), high strength, good ductility, density 16.65 kg/dm3
    Carbide graphite composite materials may be some of the hardest
    materials ever made
    Electrolytic capacitors
    Used to fabricate chemical process equipment, nuclear reactors, and
    aircraft and missile parts
    Immune to body liquids and nonirritating: therefore, widespread use
    for making surgical appliances

    Biological information

    The following gives an indication as to toxicity.
    Toxic intake: moderately poisonous by ingestion
    Lethal intake: LD50(chloride, oral, rat) = 1900 mg/kg
    Levels in humans:
    Daily dietary intake: 0.001 mg
    Total mass of element in average (70 kg person): c. 0.2 mg

    Hazards and Risks
    Tantalum compounds are encountered rarely by most people. Tantalum
    metal does not normally cause problems but all Tantalum compounds
    should be regarded as highly toxic. There are possibilities that
    Tantalum compounds cause tumors. The metal dust presents a fire and
    explosion hazard.

    Medical use: Dental implants, markers (balls, d: 0.5 to 1 mm) for
    roentgen Sterophotogrammetric analysis.
    I didn't found any information about prosthesis, screws etc. made of
    Ta. The FDA had one article about Ta-implants (Dental implant)

    Some short information form the Medline:

    Laass M et al.,(Dtsch Stomatol, 1991, 41: 12, 511-2)
    Wexler SA, et al. (Ophthalmology 92 (5): 671-675 (May 1985))
    are reporting that, there were some problems with the tissue under
    electron emission (x-ray) and Ta. Ta-parts should be removed or not

    Issa TK et al, (Am J Otol, 1983 Jul. 5: 1, 40-3)
    Conclude that Ta is tolerated by the human ear for temporal bone or

    Johansson CB. et al., (Biomaterials 11 (4): 277-280 (May 1990))
    did a qualitative interfacial study between bone and Tantalum,
    niobium or commercially pure titanium (c.p. Ti). He writes in his
    results, that there are more subtle differences between Tantalum and
    c.p. titanium than between c.p. titanium and niobium which seems to
    be less well tolerated when implanted in bone.

    Steinemann SG, (Injury 27 Suppl 3: SC16-SC22 (1996))
    Metal implants and surface reactions.
    Denatured tissue in contact with the foreign body is the consequence.
    But behaviour of metals is variable; gold, stainless steel and most
    other metals react while few others like titanium and Tantalum do

    I couldn't found jet some basic results about the biocompatibility of
    Ta. Several articles compare Ta with Titanium (Ti). The risks with
    Ta-compounds in the human body should be clearly examined, before
    using Ta-implants (prosthesis, screws) even if they are made of pure

    Beat Goepfert