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Validity of in-situ models

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  • Validity of in-situ models

    Hello, I'm a Ph.D. student focusing on Orthopaedic Biomechanics. My
    research entails modeling flatfoot versus normal-foot versus
    reconstructed-flatfoot, biomechanically.

    My question is such. How well of an approximation (percent-wise) are
    in-situ cadaver models for replicating in-vivo surgical procedures? How do
    in-vivo responses to a surgical procedure affect the biomechanics of that
    structure? For example, I will be performing Tendon Transfers and Triple
    Arthrodeses on cadavers. There normally is an in-vivo swelling response
    after surgery. How would this alter the local biomechanics of the foot
    that will not be present in a cadaver?

    None of my literature searches have lead to a plausible answer, or a
    well-educated percent estimate. If you have first-hand knowledge, or know
    of a paper discussing this issue, please forward a message to me.

    Thank you.
    ---------------------------------------------------------
    Chimba Mkandawire (Home)
    Center for Bioengineering 4317-8th Ave NE Apt. A303
    University of Washington Seattle WA, 98105
    Box 357962 206-634-3296
    Seattle, WA 98195
    206-731-4346

    http://weber.u.washington.edu/~bluntme


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