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Effect of freezing and thawing on fresh cadaver tissue properties

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  • Effect of freezing and thawing on fresh cadaver tissue properties

    Hello eveyone:

    I need some assistance from those of you who have experience working with
    "fresh" (unembalmed) cadavers or "fresh-frozen" cadavers. I am curious if
    freezing and thawing change the tissue properties measurably (especially
    ligament properties). In our lab, we are testing the creep response of
    intact ligaments in the human hand. Specifically, we receive the cadaver
    limbs frozen and then thaw them before testing. However, sometimes it
    would be convenient to do different aspects of the testing several days
    apart. The limbs stay fresher if we re-freeze them for several days and
    then re-thaw them out before the next test. But...I don't know whether or
    not the re-freezing and re-thawing effect the tissue properties. Can
    anyone help me on this one? Thanks!

    --Rick

    Richard N. Hinrichs, Ph.D.
    Dept. of Exercise Science
    Arizona State University
    Box 870404
    Tempe, AZ 85287-0404 USA
    (1) 602-965-1624 (phone)
    (1) 602-965-8108 (fax)
    Hinrichs@asu.edu (email)
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