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OpenSim Webinar: A Probabilistic Tool to Quantify Effects of Model Uncertainty

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  • OpenSim Webinar: A Probabilistic Tool to Quantify Effects of Model Uncertainty

    The OpenSim Project and the National Center for Simulation in Rehabilitation Research (NCSRR) at Stanford invite you to join our next webinar, featuring Bradley Davidson and Casey Myers from the University of Denver.

    Title: A Probabilistic Tool to Quantify the Effects of Population Variability & Model Uncertainty
    Speaker: Dr. Bradley Davidson and Casey Myers, University of Denver
    Time: Thursday, December 4, 2014 at 10:00 a.m. Pacific Daylight Time

    Uncertainty that arises from measurement error and parameter estimation can significantly affect the interpretation of musculoskeletal simulations; however, these effects are rarely addressed. The objective of this study was to develop an open-source probabilistic musculoskeletal modeling framework to assess how measurement error and parameter uncertainty propagate through a gait simulation.

    In this webinar we will:
    • Introduce underlying concepts of model uncertainty probabilistic analyses within a framework of reliability analysis
    • Provide practical examples of topics that can be addressed using probabilistic analyses in OpenSim
    • Demonstrate how to perform probabilistic analyses in OpenSim using our recently developed probabilistic plugin for OpenSim

    We will use two probabilistic approaches (Monte Carlo and Advanced Mean Value) to quantify confidence bounds, calculate sensitivity factors, and visualize the results at each stage of musculoskeletal analyses.

    We anticipate this webinar will be helpful for:
    • Biomechanical and computational researchers interested in how model uncertainty and population based variability affects simulation outputs
    • Clinicians exploring new and innovative ways to use results from population-based analysis in their research/practice
    • OpenSim users interested in adapting the tool to model problem-specific conditions

    The model, simulation files, and code used during the webinar are provided on our Simtk project page They can be used during the webinar and later as a guide to build simulation-specific probabilistic analyses.

    Participation is free, but you must register in advance. We also ask that you join the webinar 5 minutes early to orient yourself to the webinar interface.

    Visit our website for more information and registration. The website also includes links to recordings of past webinars:

    The OpenSim Webinar Series is funded by the NIH National Center for Simulation in Rehabilitation Research (NCSRR). Find out more about the NCSRR and the webinar series by visiting our website,

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