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OpenSim Webinar: Enabling Stochastic Simulations of Movement with High Throughput Com

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  • OpenSim Webinar: Enabling Stochastic Simulations of Movement with High Throughput Com

    The OpenSim Project and the National Center for Simulation in Rehabilitation Research (NCSRR) at Stanford invite you to join our next webinar, featuring Colin Smith and Darryl Thelen, University of Wisconsin-Madison.

    DETAILS

    Title: Enabling Stochastic Simulations of Movement with High Throughput Computing
    Speakers: Colin Smith and Darryl Thelen, University of Wisconsin-Madison
    Time: Thursday, November 17, 2016 at 10:00 a.m. Pacific Standard Time
    Registration:
    https://simtk.webex.com/simtk/onstag...9d0f9bafc73c41

    DESCRIPTION

    Musculoskeletal simulations of movement are traditionally performed using generic models with assumed parameters and geometries. Thus, population variability and parametric uncertainty become critically important to consider when interpreting model predictions. High Throughput Computing (HTC) systems allow thousands of independent simulations to be performed in parallel, enabling probabilistic analyses to assess the sensitivities inherent in your results. We will present an overview of HTC and an HTC enabled stochastic simulation framework developed to investigate cartilage loading in the knee during movement. We will present the results of several HTC enabled studies focusing on validation in the presence of parametric uncertainty, multifactorial sensitivity analysis and structure-function relationships. Finally, we will demonstrate how to perform OpenSim simulations on the Open Science Grid, an HTC resource freely available to US researchers (and their collaborators).

    Webinar Highlights:
    • Conceptual overview of High Throughput Computing
    • Presentation of a stochastic simulation framework to investigate knee cartilage loading during movement
    • Demonstration of how to perform your own OpenSim simulations on the Open Science Grid

    WebinarNov2016.jpg
    Figure 1.Overview of stochastic simulation framework to investigate knee cartilage loading during movement. By representing simulation parameters as probabilistic distributions, Smith, et al. are able to use High Throughput Computing to perform stochastic simulations to assess uncertainty propagation, parameter sensitivity and structure-function relationships.

    To learn more, you can refer to:

    Publications:
    • Lenhart, Rachel L., et al. "Prediction and validation of load-dependent behavior of the tibiofemoral and patellofemoral joints during movement." Annals of biomedical engineering 43.11 (2015): 2675-2685.
    • Smith, Colin R., et al. "Influence of ligament properties on tibiofemoral mechanics in walking." Journal of Knee Surgery 29.02 (2016): 099-106.
    • Smith, Colin R., et al. "The Influence of Component Alignment and Ligament Properties on Tibiofemoral Contact Forces in Total Knee Replacement." Journal of biomechanical engineering 138.2 (2016): 021017.


    Participation is free, but you must register in advance. Attendance is limited to 100. We also ask that you join the webinar 5 minutes early to orient yourself to the webinar interface.

    Visit our website for more information and registration. The website also includes links to recordings of past webinars: http://opensim.stanford.edu/support/webinars.html. The OpenSim Webinar Series is funded by the NIH National Center for Simulation in Rehabilitation Research (NCSRR). Find out more about the NCSRR and the webinar series by visiting our website http://opensim.stanford.edu.
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