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NFL Funding Opportunity for Innovative Preclinical, Translational, and Clinical Research on the Prevention, Treatment, Rehabilitation and Return-to-Play of Hamstring Injuries

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  • NFL Funding Opportunity for Innovative Preclinical, Translational, and Clinical Research on the Prevention, Treatment, Rehabilitation and Return-to-Play of Hamstring Injuries

    Program Description

    Over 850 lower body soft tissue strains occur across the NFL each year, with the majority of these injuries to the hamstring. The burden of lower extremity strains in terms of the amount of time players miss from football activities, including games, is second only to ACL tears. Recurrence of these injuries is a significant problem, as well, both in terms of time loss and financial impact to players and Clubs.

    The National Football League (the “NFL”) has developed a funding program (the “Program”) for the purposes of inviting research proposals and providing funding for innovative preclinical, translational and clinical research being conducted by leading investigative teams related to the prevention, treatment, rehabilitation, and return-to-play following injury to the hamstring muscle group.

    The goal of this Program is to provide funding support for research proposals from leading investigative teams in the field of the biology and rehabilitation of muscle injury, specifically hamstring strains. The Program will evaluate proposals that focus on either biologic therapies or primary and secondary prevention, rehabilitation, and return-to-play following hamstring strains.

    This Program’s funding opportunity is intended to facilitate the following five lines of potential inquiry: 1) Original or ongoing basic translational research activities involving the use of biologic formulations (e.g. PRP, stem cell therapies, pharmacologics) in the treatment of muscle injury using the hamstring musculature as the injury model; 2) Evidence-based clinical research exploring the use of biologic agents in the treatment of sport-related muscle injuries; 3) Development of improved prevention and injury risk mitigation strategies specific to hamstring injury; 4) Design of rehabilitation and return-to-play strategies following hamstring injury that reduce the risk of injury recurrence (secondary prevention); and 5) Innovation (e.g. micro-sensor and wearable technology, cellular-based therapies and growth factors (e.g., mesenchymal stem cells [MSCs], adipose-derived stem cells, and platelet-rich plasma [PRP]).

    The NFL’s intent through this Program is to demonstrate the potential for translational breakthroughs by leveraging innovative research, emerging science, current data sets and archival material related to the prevention, treatment, rehabilitation, and return-to-play following muscle injury, specifically, to the hamstring muscle group. This Program is designed to support multidisciplinary investigative teams with strong track records of collaboration and accomplishment in the field. New collaborations of strong research teams will be strongly considered as well.

    Funding Opportunity

    The anticipated total amount to be funded for this Program is $4,000,000. The number of winning investigative teams, and the total amount to be funded, will be determined initially based on the quality of the proposals submitted and by recommendations from the Scientific Advisory Board (SAB) (see below). The NFL will make the final decision as to which proposals are funded and to what degree based on the number of proposals recommended by the SAB.

    For complete details, please go to: https://www.playsmartplaysafe.com/re...utive-summary/
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