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Applications are invited for a enthusiastic post-doctoral researcher to join our biomechanics team at the Division of Solid Mechanics, Lund University, Sweden.
The project is entitled Statistical shape and active appearance models to improve clinical diagnostics of osteoarthritis
Type of employment: Post-doctoral researcher, min 1.5 years, 100 %
Starting date: As soon as possible
Responsible: Assoc Prof Hanna Isaksson
Salary is defined according to the salary system of Lund University.
Project.
Background: Osteoarthritis is a musculoskeletal disease that involves progressive degeneration of the articular cartilage in e.g. the hip and knee joints. Current diagnostics is largely based on radiography and visual examination. Unfortunately, they cannot detect the early signs of osteoarthritis. When the disease is detectable, the damage is already irreversible. Hence, novel methods are needed. By combining engineering, mechanical modeling and medical imaging, a new method is proposed.
Objective: This project aim to develop a method that can potentially improve diagnosis of osteoarthritis by accounting for and predicting geometrical features that may be related to development of osteoarthritis.
Approach: The method is based on integrating functional imaging of the hip bone based on radiographs with statistical shape modeling using active appearance model. From a 2D radiographic image, the method will be able to estimate the geometry of the bone fully in 3D. This allows quantification of geometrical shape parameters known to be related to development of osteoarthritis, and the patients individual rotation of the hip. The method will be validated with images from two clinical studies; one focusing on geometrical parameters related to development of osteoarthritis and one related to pre-operative planning during hip replacement surgery. If successful, the method may have significant scientific and socio-economic impact.
Research environment.
The project involves primarily computational work. The research will be done at the Division of Solid Mechanics, and Department of Orthopedics, Lund University, but is part of a collaborative project with University of Eastern Finland, Kuopio, and Erasmus Medical Center, Rotterdam.
Requirements.
Applications are invited from interested and motivated researchers with a PhD in engineering/physics/mathematics. Suitable background include biomedical engineering, medical physics, mechanical engineering, mathematics, or other relevant fields. Experience in image processing methods, shape and appearance modeling, optimization and matlab programming is highly advantageous. Moreover, ability to express yourselves in English in speech and writing is a requirement, and the ability to work independently is considered highly important.
Information.
Applications.
Interested candidates are invited to contact Dr Hanna Isaksson and to submit their applications (please include letter of motivation, CV, publication list, degree certificate, and name and contact information to at least one referee) to hanna.isaksson@solid.lth.se
Contact details.
For more information, questions, or correspondence, please contact:
Hanna Isaksson, Ph.D, Associate Professor Solid Mechanics / Orthopedics
Lund University, Box 118, 221 00 Lund, Sweden.
Email: hanna.isaksson@solid.lth.se, Phone: +46 46 22 24423
The project is entitled Statistical shape and active appearance models to improve clinical diagnostics of osteoarthritis
Type of employment: Post-doctoral researcher, min 1.5 years, 100 %
Starting date: As soon as possible
Responsible: Assoc Prof Hanna Isaksson
Salary is defined according to the salary system of Lund University.
Project.
Background: Osteoarthritis is a musculoskeletal disease that involves progressive degeneration of the articular cartilage in e.g. the hip and knee joints. Current diagnostics is largely based on radiography and visual examination. Unfortunately, they cannot detect the early signs of osteoarthritis. When the disease is detectable, the damage is already irreversible. Hence, novel methods are needed. By combining engineering, mechanical modeling and medical imaging, a new method is proposed.
Objective: This project aim to develop a method that can potentially improve diagnosis of osteoarthritis by accounting for and predicting geometrical features that may be related to development of osteoarthritis.
Approach: The method is based on integrating functional imaging of the hip bone based on radiographs with statistical shape modeling using active appearance model. From a 2D radiographic image, the method will be able to estimate the geometry of the bone fully in 3D. This allows quantification of geometrical shape parameters known to be related to development of osteoarthritis, and the patients individual rotation of the hip. The method will be validated with images from two clinical studies; one focusing on geometrical parameters related to development of osteoarthritis and one related to pre-operative planning during hip replacement surgery. If successful, the method may have significant scientific and socio-economic impact.
Research environment.
The project involves primarily computational work. The research will be done at the Division of Solid Mechanics, and Department of Orthopedics, Lund University, but is part of a collaborative project with University of Eastern Finland, Kuopio, and Erasmus Medical Center, Rotterdam.
Requirements.
Applications are invited from interested and motivated researchers with a PhD in engineering/physics/mathematics. Suitable background include biomedical engineering, medical physics, mechanical engineering, mathematics, or other relevant fields. Experience in image processing methods, shape and appearance modeling, optimization and matlab programming is highly advantageous. Moreover, ability to express yourselves in English in speech and writing is a requirement, and the ability to work independently is considered highly important.
Information.
Applications.
Interested candidates are invited to contact Dr Hanna Isaksson and to submit their applications (please include letter of motivation, CV, publication list, degree certificate, and name and contact information to at least one referee) to hanna.isaksson@solid.lth.se
Contact details.
For more information, questions, or correspondence, please contact:
Hanna Isaksson, Ph.D, Associate Professor Solid Mechanics / Orthopedics
Lund University, Box 118, 221 00 Lund, Sweden.
Email: hanna.isaksson@solid.lth.se, Phone: +46 46 22 24423