The INSIGNEO Institute for in silico Medicine is an initiative between the Faculty of Engineering and the Faculty of Medicine at the University of Sheffield and the Sheffield Teaching Hospitals Foundation Trust. INSIGNEO intends to realise the scientific ambition behind the Virtual Physiological Human, producing a transformational impact on healthcare. While recently established, INSIGNEO is already considered one of worldwide-leading institutions in the area of in silico medicine research. For more information on INSIGNEO please see our web pages:

Mechanical Engineering has been a major discipline in the University since its foundation in 1905. In the most recent Research Assessment Exercise (December 2008), the Department came second in the country in the league table of Mechanical Engineering departments, and achieved an "Excellent" rating in the last Teaching Quality Assessment. There are currently 104 members of staff and over 540 undergraduates and 200 postgraduate students. The Department is located in the Sir Frederick Mappin Building on the St George’s site, adjacent to the other Engineering departments. For more information on the Department please see our web site

This is an excellent research opportunity within the musculoskeletal modelling of the INSIGNEO Institute for in silico Medicine. The research forms part of a five year programme to create a new modelling framework for the human musculoskeletal system. The engineering-based model of an individual patient’s musculoskeletal makeup will be able to reduce soaring treatment costs for chronic bone disorders by predicting disease development and enabling better treatment. It will simultaneously capture processes at a cellular scale right up to the whole body.

The £6.7M Frontier Engineering grant from the Engineering and Physical Sciences Research Council (EPSRC) – awarded to the world leading and innovative INSIGNEO Institute – will improve treatments for diseases of the musculoskeletal system.

One post-doc position associated to the Frontier grant is now open:

• Research Associate in musculoskeletal biomechanics

The post-doc will be work under the supervision of Prof. Marco Viceconti.and Dr Claudia Mazzà

For more details: