Job Description

A post-doctoral research fellowship position is available in the Neural Engineering Laboratory at Mayo Clinic to study and model neurotransmitter efflux evoked by deep brain stimulation (DBS). This NIH-supported research will specifically examine the biophysical interaction of electrical stimulation and neurotransmitter efflux across neural circuits associated with DBS treatment of movement and psychiatric disorders.


The research fellow will be expected to analyze and model real-time neural activity and neurotransmitter efflux evoked by deep brain stimulation (DBS). Responsibilities will include real-time acquisition and processing of neural signals, computational modeling of neurotransmitter dynamics, as well as the development and implementation of neuromodulation control strategies. The research involves the use of neurostimulation systems, neurotransmitter recording sensors, as well as anatomical and functional imaging in a multidisciplinary environment. Additional responsibilities will include development and validation of in vitro and in vivo models of DBS. The Fellow will be expected to independently design and execute experiments, analyze and interpret data, assist in the preparation of grants and manuscripts, participate in lab meetings, present findings at scientific meetings, and train students and new personnel. The successful candidate will be a highly motivated individual with a demonstrated record of accomplishments, including a strong publication record.

Basic Qualifications:

· Ph.D. degree in Neural Engineering, Biomedical Engineering, Electrical Engineering, Computational Neuroscience, or Control Systems Engineering.
· Proficiency in real-time signal acquisition, multivariate signal analysis, feature extraction, control systems engineering, and algorithm development.
· Experience with analytical and statistical software packages (e.g., Matlab, LabView, R, etc.), and/or programming languages (e.g., C++).
· High level of initiative, and ability to independently plan, execute, and troubleshoot experimental designs.
· Ability to work as part of an interdisciplinary team (including physicians, biologists, chemists, engineers, technicians, and veterinarians).
· Excellent communication and documentation skills.
· Ability to multi-task and maintain a high level of organization and professionalism.

Please attach the following required documents at the time of application:

1. Current curriculum vitae, bibliography, and cover letter outlining current and future research interests
2. Three letters of recommendation, signed, on letterhead, describing:
a. Relationship to the applicant.
b. Past work/academic performance.
c. Work qualities/personal conduct.
d. Overall assessment of potential for success in research environment.
3. Doctoral degree certification. If applicable, submit original or notarized copy of diploma or final transcript issued by school (English translation required).

Other Qualifications:

· Strong background and/or interest in experimental/computational/clinical neuroscience, neuromodulation technology (e.g., deep brain stimulation (DBS), functional electrical stimulation (FES)), and brain computer interfaces (BCI).
· Working knowledge of neurophysiology and neurochemistry, particularly electrophysiological activity recordings and electrochemical detection of neurotransmitters (e.g., using fast scan cyclic voltammetry and amperometry).
· Experience with large animal models of behavior (e.g., models of Parkinson’s disease).

Contact Information:

Interested applicants should submit a brief cover letter outlining current and future research interests, a CV, and three recent letters of reference at:

For more information, please contact Luis Lujan, Ph.D. (, Assistant Professor, Departments of Neurologic Surgery and Physiology & Biomedical Engineering, College of Medicine, Mayo Clinic.

Company Statement:

Mayo Clinic is known nationally and internationally for outstanding achievements in patient care, research and education. Mayo Clinic is a not-for-profit, integrated group practice focusing on high quality, compassionate medical care. Multi-disciplinary teams work together to care for patients, joined by common systems and a philosophy of “the needs of the patient come first.” Mayo Clinic has sites in Minnesota, Arizona and Florida. Temporary Professional positions provide opportunities for post-doctoral training and education, as well as opportunities to gain expertise in specialized areas by working with established research investigators.

Equal Opportunity Employer:

Mayo Clinic is an equal opportunity educator and employer (including veterans and persons with disabilities).