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PhD student positions in orthopaedic and tissue biomechanics

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  • PhD student positions in orthopaedic and tissue biomechanics

    PhD student positions in orthopaedic and tissue biomechanics

    Type of employment: PhD student, 4 years
    Host institution: University of Eastern Finland, Kuopio, Finland

    Ultimate goal
    • Develop and validate models of bone and cartilage adaptation to loading, and apply them in patient-specific knee joint geometries for the evaluation of the progression of osteoarthritis (effects of treatments and operations will be tested).

    Mechanical properties and structure of bones, menisci and ligaments are determined and implemented in the biomechanical model of the knee joint. The model is validated against extensive experimental data (e.g. motion analysis, clinical imaging of cartilage deformations). The model with algorithms for cartilage and bone adaptation to loading will be validated against experimental data of the altered cartilage and bone properties and/or osteoarthritis grade (in vitro, in situ, humans in vivo). The effect of different tissue injuries (e.g meniscus tear), treatments and operations (e.g. weight loss, partial meniscectomy) on knee joint stresses and osteoarthritis progression of patients will be evaluated.

    PhD student position #1, experimental
    Determine time-dependent mechanical properties and structure of bones, menisci and ligaments. Conduct in vitro and/or in vivo experiments to simulate and follow up the progression of post-traumatic osteoarthritis. This includes laboratory experiments as well as obtaining clinical imaging and motion analysis data of patients. This data is later used for model validation and input.

    PhD student position #2, computational
    Evaluate the importance of realistic bone and soft tissue properties in the models of knee joints on cartilage and chondrocyte responses. Develop and validate computational models of the knee joint with adaptive properties of articular cartilage and bone, and predict the effect of abnormal loading on altered cartilage and bone properties during the progression of osteoarthritis. Aforementioned experimental data is used for model validation.

    We are looking for highly motivated candidates with the background in one or several of the following or related disciplines; biomedical engineering, biomechanics, medical physics, mechanical engineering, or related field. For the PhD student position #2, good modeling skills and experience in the use of Abaqus and user materials are advantages. All studies will be conducted in close collaboration with post docs and collaborators. Therefore, good collaborative attitude is needed in both positions.

    The research projects include both national and international collaboration with several internationally recognized research groups in their own field. Research mobility is highly supported.

    To apply, e-mail your CV, list of publications, study record, degree certificate and application letter describing why you are interested in this position to no later than on August 31st 2015. Include also names and contact information of 2-3 references.

    Contact details
    For further information, please contact Associate Professor Rami Korhonen (,