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PhD position, connective tissue characterization, @LBMC, Univ Lyon, FRANCE

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  • PhD position, connective tissue characterization, @LBMC, Univ Lyon, FRANCE

    I am seeking a highly motivated PhD student with a background in biomechanics, physics, mechanical engineering, or biomedical engineering.

    The thesis project is about the characterization of connective tissue (fascia) mechanical properties, and is entitled
    Characterization of fascia mechanical properties for clinic and virtual human":

    Musculoskeletal disorders are becoming more and more common in our sedentary life. They are most often due to muscular tension and can in some extreme cases lead to chronic and disabling pain. But, are only our muscles involved in this pain?
    Muscles, like most organs and structures in the body are surrounded by fascias. Fascia is a connective tissue composed of collagen and elastin fibers, which may be loose or dense depending on its role. Here, we are interested in dense fascia whose main function is to sheath muscle (aponeurosis) and muscle groups (such as fascia lata). It also contributes to joints stability and to force transmission between muscles. However, its behavior remains not very well-known.

    Literature reports few in vitro studies dealing with the characterization of fascia mechanical properties. They point out its anisotropic, non-linear and viscoelastic behavior. The most advanced works in this area consist in unidirectional and biaxial tensile tests on goat fascia lata and proposed an associated constitutive law. Nevertheless, this modeling assumes a homogeneous strain of the tissue, does not take into account the effects of shear, and neglects the viscoelastic behavior while stresses applied to the tissue are quite far from the physiological loadings.

    The main objective of this work is thus the characterization of fascia mechanical properties and of its mechanical effect in force transmission between muscles, in particular with the study of the pre-stress exerted by fascia on muscular tissue.

    Keywords : Biomechanics, fascia, experimentation, constitutive law, modeling

    Full description of the project (in both french and english):
    Laboratoire de Biomécanique et Mécanique des Chocs Université Gustave Eiffel 25 avenue François Mitterrand, Case24 Cité des mobilités...

    Application deadline : 31st of May, 2017

    For more information : please contact Laure-Lise Gras,
    and visit the lab website :

    Laure-Lise Gras
    Maître de conférences / Assistant Professor
    LBMC UMR_T9406
    Laboratoire de Biomécanique et Mécanique des Chocs
    Université Lyon 1 - IFSTTAR