Postdoctoral Research Associate in Cell and Tissue Multiscale Modelling at Insigneo

[Enrico Dall'Ara]

Job Title: Postdoctoral Research Associate in Cell and Tissue Multiscale Modelling
Project Title: A Multiscale Bone Remodelling Predictor for Discovering Innovative Therapies to Osteoporosis
Related Project: MULTISIM (PI: Prof Damien Lacroix; http://multisim-insigneo.org/)
Description:
The goal is to expand an in-house agent-based model (ABM) simulating cellular activity during osteogenesis, and to couple this model with a finite element (FE) model of bone tissue.

The post holder will work towards developing dynamic multi-scale bone remodelling units in the tibia responding to biomechanical stimulations under physiological and pathological conditions. A combined agent-based model (ABM) and finite element (FE) framework will be utilised to simulate signalling networks, including that of the parathyroid hormone (PTH), and monitor their influence on cell-cell interaction and emergent behaviour. The models will be integrated into a hypermodelling framework that consists of several sub-models at various scales (cell, tissue, organ, body) so that an overall musculoskeletal model can be generated
Supervisors: Dr Aban Shuaib and Dr Enrico Dall’Ara
Contact: e.dallara@sheffield.ac.uk; aban.shuaib@sheffield.ac.uk
Start position: as soon as possible
Duration: until 31st August 2018
Closing application: 10 Sep 2017
Salary: Grade 7; £30,175 to £38,183 per annum

Application number: UOS017097
Link Application:

https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_unreg_job_search?sap-client=400&sap-syscmd=nocookie&sap-wd-configId=ZHRRCF_A_UNREG_JOB_SEARCH&sap-ie=edge&utm_source=university%20website&utm_medium=link&utm_content=jobs&utm_campaign=jobs-link#

Enrico Dall'Ara