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The Laboratory of Bone Biomechanics headed by Dr. Alessandra Carriero in the Department of Biomedical Engineering at The City College of New York, is offering two PhD Positions in the field of Bone Multiscale Mechanics and Mechanobiology.
Dr. Carriero’s research focuses on providing a comprehensive understanding of bone mechanics and adaptation in healthy, ageing and disease so to aid in the development of new treatment strategies for bone frailty and deformities. Dr. Carriero’s lab uses mechanical engineering methods, material science approaches, high-resolution imaging, clinical data and biological analysis to reveal how mechanical forces influence bone growth, maintenance and function. Bone fragility is a very common but yet not well understood. Understanding the mechanisms of bone failure in frailty has potential to make a significant positive impact on the quality of life of people worldwide, while delivering economic benefits to our society.
Position 1: This research will contribute to understanding the effect of ageing and disease on the composition, structure and mechanical properties of bone along its hierarchy and its impact on whole bone fracture toughness. The specific aims of this PhD project are to 1) develop novel high-resolution imaging acquisition and analysis for bone composition and structure, while simultaneously conduct fracture mechanics tests in healthy, disease and treated bone; (2) assess local bone measurements with biomarkers and compare these to the structure/composition and mechanics of bone; (3) develop new multiscale modelling approaches to evaluate fracture resistance in brittle bones and treatments.
Position 2: This research will contribute to understanding of hearing loss in osteogenesis imperfecta (or brittle bone disease). The specific aims of this PhD project are to 1) develop novel high-resolution imaging acquisition analysis for cochlea micromechanics; (2) assess bone and soft tissue structure, composition and mechanics; (3) develop modeling approaches to evaluate cochlea mechanics in healthy, disease and treated conditions.
Both positions will be based at at The City College of New York, where the candidates will be enrolled in the Doctorate Program in Biomedical Engineering, and research will be conducted in collaboration with other instistutions in US and UK, particularly Hospital for Special Surgery, Northwestern University, Imperial College and the Diamond Light Source.
The successful candidate holds or will soon receive a Master’s or an equivalent Degree in Biomedical Engineering, Mechanical Engineering, Physics, Materials Science or Mathematics. A high motivation to work in a pioneering research environment at the interface between engineering, science and medicine is essential as well as the enthusiasm to work in an international and multidisciplinary team. Availability to travel and work with animals is required. Good knowledge of English (oral and written) is essential. Experience in one or more of the following is desirable: biomedical research, mechanical testing, experimental testing of bone, imaging acquisition, imaging processing, computational modelling techniques.
We look forward to receiving your application including a motivation letter, CV, university transcripts and names and contact details of three references. Applications must be submitted through our CCNY website at https://app.applyyourself.com/AYAppl...p?id=CUNYCCNYG by January 15 and confirmed by email to Dr. Carriero at acarriero@ccny.cuny.edu. More information about the application procedure can be found at https://www.ccny.cuny.edu/admissions/graduate-studies. For international students, GRE and/or TOEFL can be submitted by March 1 2019. While there is no minimum score for the GRE and/or TOEFL, it is however expected that the scores demonstrate aptitude for graduate research. The positions are available immediately and will last until filled.
For further information about the positions, please contact Dr. Alessandra Carriero at acarriero@ccny.cuny.edu.
Dr. Carriero’s research focuses on providing a comprehensive understanding of bone mechanics and adaptation in healthy, ageing and disease so to aid in the development of new treatment strategies for bone frailty and deformities. Dr. Carriero’s lab uses mechanical engineering methods, material science approaches, high-resolution imaging, clinical data and biological analysis to reveal how mechanical forces influence bone growth, maintenance and function. Bone fragility is a very common but yet not well understood. Understanding the mechanisms of bone failure in frailty has potential to make a significant positive impact on the quality of life of people worldwide, while delivering economic benefits to our society.
Position 1: This research will contribute to understanding the effect of ageing and disease on the composition, structure and mechanical properties of bone along its hierarchy and its impact on whole bone fracture toughness. The specific aims of this PhD project are to 1) develop novel high-resolution imaging acquisition and analysis for bone composition and structure, while simultaneously conduct fracture mechanics tests in healthy, disease and treated bone; (2) assess local bone measurements with biomarkers and compare these to the structure/composition and mechanics of bone; (3) develop new multiscale modelling approaches to evaluate fracture resistance in brittle bones and treatments.
Position 2: This research will contribute to understanding of hearing loss in osteogenesis imperfecta (or brittle bone disease). The specific aims of this PhD project are to 1) develop novel high-resolution imaging acquisition analysis for cochlea micromechanics; (2) assess bone and soft tissue structure, composition and mechanics; (3) develop modeling approaches to evaluate cochlea mechanics in healthy, disease and treated conditions.
Both positions will be based at at The City College of New York, where the candidates will be enrolled in the Doctorate Program in Biomedical Engineering, and research will be conducted in collaboration with other instistutions in US and UK, particularly Hospital for Special Surgery, Northwestern University, Imperial College and the Diamond Light Source.
The successful candidate holds or will soon receive a Master’s or an equivalent Degree in Biomedical Engineering, Mechanical Engineering, Physics, Materials Science or Mathematics. A high motivation to work in a pioneering research environment at the interface between engineering, science and medicine is essential as well as the enthusiasm to work in an international and multidisciplinary team. Availability to travel and work with animals is required. Good knowledge of English (oral and written) is essential. Experience in one or more of the following is desirable: biomedical research, mechanical testing, experimental testing of bone, imaging acquisition, imaging processing, computational modelling techniques.
We look forward to receiving your application including a motivation letter, CV, university transcripts and names and contact details of three references. Applications must be submitted through our CCNY website at https://app.applyyourself.com/AYAppl...p?id=CUNYCCNYG by January 15 and confirmed by email to Dr. Carriero at acarriero@ccny.cuny.edu. More information about the application procedure can be found at https://www.ccny.cuny.edu/admissions/graduate-studies. For international students, GRE and/or TOEFL can be submitted by March 1 2019. While there is no minimum score for the GRE and/or TOEFL, it is however expected that the scores demonstrate aptitude for graduate research. The positions are available immediately and will last until filled.
For further information about the positions, please contact Dr. Alessandra Carriero at acarriero@ccny.cuny.edu.