Knee internal contact forces in the knee osteoarthritis population

Knee osteoarthritis (KOA) is a heterogeneous pathology characterized by a complex and multifactorial nature. The identification of KOA phenotypes (i.e. subgroups of patients characterized by distinct disease mechanisms) would allow for targeted treatment and enhance treatment effects, which may otherwise be lost when looking at KOA as a whole.

This webcast details the methods employed to identify biomechanical phenotypes characterized by alteration in the knee internal contact forces. Thirty-nine KOA patients and 18 controls were analyzed for the purpose of the study. Knee frontal alignment and MRI cartilage semi quantitative scores were used to classify the participants in subgroups characterized by different disease patterns (e.g. varus malalignment and medial OA, varus malalignment and bicompartmental OA). Kinematic data were collected at the Innovation Human Laboratory of Glasgow Caledonian University. The Twente lower extremity model (TLEM) was used to estimate the participants knee internal contact forces.


Andrea Dell'Isola, Lecturer in Biomechanics, Edinburgh Napier University


The presentation will be made twice Tuesday, 3 April 2018. Seating is limited, so sign up now