To the group:

I am currently tracking down information on the use of Fuji film to
measure pressure distribution within the rabbit knee. An exploration of
the Biomch-l archives created some further questions in that regard.

In January of 1996, Amy Lerner posted a summary of results about her
inquiry into measuring pressure in the rabbit hind limb. At that time,
very little had been done with rabbits, with most research concentrating
on goats and dogs. QUESTION 1: Has anyone since then (or Lerner
herself) come up with a suitable methodology to measure pressure within
the rabbit knee that provides meaningful and repeatable results?
QUESTION 2: If so, is/are there publication/s that describe that
methodology?

In that same review posting, Matthew Allen (mja@vet.vet.purdue.edu)
metioned a group in Bristol, England that did have such a methodology
for using Fuji film using a goat model. However, no mention was ever
made of who belonged to this group or where publications might be found.
QUESTION 3: Is anyone familiar with who this Bristol group might be
and where they could be reached via email?

In February of this year, Eric Eils inquired as to shareware to
perform an analysis of grey scale image, mean grey scale and total
pressure area on the film. No response has been posted to the availability
of this type of software. I am aware that some packages might do similar
functions (NIH Image and Osiris if I recall). QUESTION 4: Does such a
package exist; and if it is shareware, where could I find it?

I have several other general questions, which I did not have when I
performed the initial search and will present them here. QUESTION 5: Are
there problems storing the films in a cool dark place for long periods of
the time? QUESTION 6: Can films be stacked up one another after they have
been sufficiently secured to prevent slipping/shear? QUESTION 7: Are there
problems when using the films in certain fluids (water/saline/bovine serum)?

I am aware that answers may be found in a PubMed search. An initial search
did discover some papers that may be useful, but the search did not locate
the papers mentioned above. I appreciate any information people could
provide on the methodolgy for measuring within knee pressures in a rabbit
model using Fuji film. I will post a summary of all replies at some point.

Take care all.

Andrew

Andrew Mahar, M.S.
Biomechanical Engineer
Orthopedic Biomechanics Research Center

MC 5054
3020 Children's Way
San Diego, CA 92109

Lab 1: 619-495-4975
Lab 2: 619-452-0192
Pager: 619-493-3174
Fax: 619-614-7494
Email: amahar@chsd.org

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